Table of Contents
- Butylparaben Technical Specifications
- Industrial Applications & Functional Advantages
- Optimal Usage Parameters & Safety Protocols
- Implementation Case Studies
- Verified Client Applications
- Technical Consultation & Ordering
Butylparaben (CAS 94-26-8) Technical Specifications
Chemical Profile
| Parameter | Specification | Methylparaben | Propylparaben |
|---|---|---|---|
| Molecular Formula | C11H14O3 | C8H8O3 | C10H12O3 |
| Molecular Weight | 194.23 g/mol | 152.15 g/mol | 180.20 g/mol |
| Preservative Efficacy | Broad-spectrum (Gram+/-, fungi) | Bacteriostatic | Yeast inhibition |
| pH Stability | 3.0-8.0 | 3.0-6.5 | 4.0-7.5 |
Key Differentiators
- Superior oil solubility vs shorter-chain parabens
- 0.1-0.3% effective concentration range
- Synergistic action with other preservatives
Industrial Applications & Functional Advantages
Core Functional Properties
- Pharmaceutical-grade antimicrobial preservation
- Oxidation resistance in lipid-based formulations
- Plasticizer compatibility in polymer matrices
Application Matrix
| Industry | Typical Concentration | Functional Benefit |
|---|---|---|
| Cosmetic Emulsions | 0.15-0.25% | Phase-stable preservation |
| Topical Ointments | 0.08-0.15% | API protection |
| Industrial Coatings | 0.3-0.5% | Biocide enhancement |
Optimal Usage Parameters & Safety Protocols
Formulation Best Practices
- Combine with ethylhexylglycerin for boosted efficacy
- Pre-dissolve in heated oil phase (60-70°C)
- Maintain pH below 8.0 to prevent hydrolysis
Regulatory Compliance
- EU Cosmetic Regulation (EC) No 1223/2009 compliant
- FDA 21 CFR 175.300 compliant for indirect food contact
- REACH registered
Implementation Case Studies
Case 1: Anti-Aging Cream Preservation
- Challenge: Microbial contamination in water-in-oil emulsion
- Solution: 0.2% butylparaben + 0.5% phenoxyethanol blend
- Result: 24-month stability at 40°C/75% RH
Case 2: Transdermal Patch Preservation
- Challenge: API degradation in matrix system
- Solution: 0.1% butylparaben in adhesive layer
- Result: Microbial counts <10 CFU/g throughout 36-month shelf life
Verified Client Applications
Client A: European Cosmetic Manufacturer
- Application: Sunscreen SPF 50+ formulation
- Usage: 0.18% in oil phase
- Outcome: PASS in ISO 29621 challenge test
Client B: Pharmaceutical Contract Manufacturer
- Application: Hydrocortisone cream USP
- Usage: 0.12% with EDTA
- Outcome: Compliant with USP <51> preservative effectiveness
Technical Consultation & Ordering
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Ordering Information
| Package | Purity | MOQ |
|---|---|---|
| Lab Sample | 99.5% | 100g |
| Industrial Grade | 99.0% | 25kg |
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