3-Hydroxybenzaldehyde (CAS 100-83-4): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification | Comparison with Analogues |
|---|---|---|
| Chemical Name | 3-Hydroxybenzaldehyde (m-Hydroxybenzaldehyde) |
Distinct hydroxyl positioning vs. o-/p-isomers |
| CAS No. | 100-83-4 | Unique identifier per IUPAC |
| Molecular Formula | C7H6O2 | Same as benzaldehyde derivatives |
| Molecular Weight | 122.12 g/mol | Lower than brominated derivatives |
| Appearance | Colorless to pale yellow crystals | Similar to phenolic aldehydes |
| Melting Point | 102-105°C | Higher than vanillin (80-81°C) |
| Boiling Point | 191°C at 50 mmHg | Lower volatility than benzaldehyde |
| Solubility | Sparingly in water Miscible with ethanol, acetone, ether |
Better organic solubility than salicylaldehyde |
2. Key Applications & Industrial Uses
Pharmaceutical Intermediates
Core component in synthesis of:
- Roxatidine acetate hydrochloride (anti-ulcer agent)
- Schiff base pharmaceuticals
- Antimicrobial drug precursors
Specialty Chemicals
- Photoemulsion additives for silver halide photography
- High-performance dye intermediates
- Polymer modification agents
Analytical Chemistry
- Chromogenic agent in Schiff’s reagent formulations
- Metal ion chelation studies
3. Manufacturing Process Comparison
| Process | Traditional Method | Advanced Synthesis |
|---|---|---|
| Starting Material | m-Nitrobenzaldehyde | m-Cresol derivatives |
| Key Steps | 1. Bisulfite addition 2. Iron reduction 3. Diazotization |
Catalytic hydroxylation Oxidative coupling |
| Yield | 68-72% | 82-85% |
| Environmental Impact | High wastewater generation (COD >5,000 mg/L) |
Closed-loop solvent recovery (COD <800 mg/L) |
| Purity | 97-98% | 99.5%+ |
4. Safety & Handling Guidelines
Hazard Classification
- Xi – Irritant (R36/37/38)
- WGK 3 – Water hazard class
Protective Measures
- PPE: Nitrile gloves, chemical goggles
- Ventilation: Local exhaust required
- Storage: Amber glass in cool (<25°C), dry conditions
Emergency Protocols
- Eye contact: Flush with saline ≥15 minutes
- Skin exposure: Wash with 5% sodium bicarbonate
- Spill management: Absorb with vermiculite
5. Industry Implementation Cases
Case 1: Pharmaceutical Synthesis
Client: EU-based API manufacturer
Application: Roxatidine intermediate scale-up
Result: Achieved 92% yield through optimized diazotization at 5°C
Case 2: Agrochemical Production
Client: Asian crop protection company
Application: Fungicide synergist development
Result: Enhanced bioactivity by 40% vs. o-isomer
Case 3: Advanced Materials
Client: US polymer research institute
Application: Epoxy resin modification
Result: Improved thermal stability (Tg +18°C)
6. Technical Inquiry & Ordering
For product specifications, MSDS, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Technical support available for formulation optimization and custom synthesis.
相关产品
Common English name: 5-iodo-2,3-dihydropyridazin-3-one
CAS No.: 825633-94-1
Molecular formula: C4H3IN2O
Molecular weight: 221.98
Sample: Available
Chemical Name: 3-Hydroxybutyric acid
CAS No.: 625-71-8
Molecular Formula: C4H8O3
Molecular Weight: 104.1
Appearance: White powder
Chemical Name: Dehydrocholic acid
Synonyms: Acide dehydrocholique; Triketocholanic acid
CAS No.: 81-23-2
Molecular Formula: C24H34O5
Molecular Weight: 402.53
Appearance: Powder
Chemical Name: Ethyl Hexanoate
Synonyms: Ethyl caproate; Caproic acid ethyl ester; Ethyl butyl acetate; capronic ether; hexanoic acid ethyl ester
CAS No.: 123-66-0
Molecular Formula: C8H16O2
Molecular Weight: 144.21
Chemical Name: D-PANTOTHENIC ACID
CAS No.: 79-83-4
Molecular Formula: C9H17NO5
Molecular Weight: 219.24
Appearance: Colorless or Light Yellow Oily Liquid
Chemical Name: alpha-Hexylcinnamaldehyde
CAS No.: 101-86-0
Molecular Formula: C15H20O
Molecular Weight: 216.32
Appearance: Yellow Liquid
Chemical Name: N-(3-Aminopropyl)morpholine
CAS No.: 123-00-2
Molecular Formula: C7H16N2O
Molecular Weight: 144.21
Appearance: Colorless transparent liquid
Chemical Name: 3-Chloroaniline
Synonyms: 1-Amino-3-chlorobenzene; m-Aminochlorobenzene; 3-Chlorobenzenamine; 3-Chlorophenylamine
CAS No.: 108-42-9
Molecular Formula: C6H6ClN
Molecular Weight: 127.57
Appearance: Colorless Liquid
Chemical Name: D-Phenothrin
CAS No.: 26046-85-5
Molecular Formula: C23H26O3
Molecular Weight: 350.45
Appearance: Oil
Chemical Name: D-PANTOTHENIC ACID
CAS No.: 79-83-4
Molecular Formula: C9H17NO5
Molecular Weight: 219.24
Appearance: Colorless or Light Yellow Oily Liquid
Chemical Name: Di-n-amyl disulfide
Cas No.: 112-51-6
Molecular Fomula: C10H22S2
Molecular Weight: 206.41
Chemical Name: Potassium Castorate
CAS No.: 8013-05-6
Molecular Formula: C57H107K3O12
Molecular Weight: 1101.74718
Appearance: Yellow Liquid
评论
目前还没有评论。