FMOC-DAB BOC-OH CAS 125238-99-5

Directory

• Product Overview & Specifications
• Detailed Applications
• Usage Guidelines
• Case Studies
• Client Success Stories
• Contact for Technical Support

FMOC-DAB(BOC)-OH CAS 125238-99-5: Product Overview & Specifications

Key Parameters

Structural Advantages

FMOC-DAB(BOC)-OH features dual protection:
– FMOC group: Enables orthogonal deprotection
– BOC group: Enhances acid stability
Molecular Formula: C₂₅H₂₈N₂O₆

Detailed Applications in Pharmaceutical Research

Core Functions

1. Peptide synthesis intermediate for:
 • HIV protease inhibitors
 • Cancer-targeting peptides
2. Building block for:
 • Antibody-drug conjugates (ADCs)
 • GPCR ligand development

Industry-Specific Uses

Biopharma: Enables precise control in solid-phase synthesis
Diagnostics: Critical for fluorescent probe conjugation
Academic Research: Facilitates structure-activity relationship studies

Optimized Usage Protocols

Recommended Workflow

1. Deprotection: 20% piperidine/DMF (30 min)
2. Coupling: HBTU/DIEA activation (2 hrs)
3. Wash cycle: 3× DCM, 3× methanol

Quality Control

Batch-specific certificates include:
– Mass spectrometry reports
– Chiral purity analysis
– Residual solvent profiles

Synthesis Case Studies

Case 1: Antiviral Peptide Development

Client: European Biotech Startup
Challenge: Required 99% chiral purity for protease-resistant sequence
Solution: Optimized FMOC-DAB(BOC)-OH coupling at 0.5M concentration
Outcome: Achieved 98.7% yield with <1% epimerization

Case 2: ADC Linker Construction

Client: US Pharma Leader
Challenge: Needed acid-stable intermediate for payload attachment
Solution: Implemented BOC-protected amine during conjugation
Result: Improved conjugate stability by 40% vs. standard Fmoc-amino acids

Verified Client Success Stories

PharmaTech Solutions

Location: Cambridge, UK
Application: Peptide nucleic acid (PNA) synthesis
Volume: 5kg/year contract
Feedback: “Reduced synthesis steps from 12 to 8 stages”

BioSynth Laboratories

Location: Shanghai, China
Application: Custom amino acid derivatives
Volume: Batch orders of 500g-2kg
Feedback: “Consistent ≥98.5% purity across 14 batches”

Technical & Commercial Consultation

Expert Support Available

Our peptide chemistry specialists provide:
– Custom synthesis protocols
– Regulatory documentation support
– Scale-up feasibility studies

Contact Information

Email: info@vivalr.com
Phone: (86) 15866781826
Service Hours: Mon-Fri 08:00-17:00 GMT+8

Request product dossier containing:
– Stability data (0-24 months)
– Safety data sheets
– References from peer-reviewed publications