Trifluoroacetic anhydride/TFAA Cas 407-25-0

Chemical Name: Trifluoroacetic anhydride, TFAA
Assay:≧99.0%
Appearance: Colorless liquid
Packaging:250 Kg/drum
Sample: available
related documents:

COA of Trifluoroacetic Anhydride
TDS of Trifluoroacetic Anhydride

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Trifluoroacetic Anhydride (TFAA) CAS 407-25-0: Comprehensive User Guide

1. Product Overview & Specifications

Parameter TFAA Conventional Acetic Anhydride
CAS Number 407-25-0 108-24-7
Molecular Formula C4F6O3 C4H6O3
Molecular Weight 210.03 g/mol 102.09 g/mol
Boiling Point 39.5-40°C 139.8°C
Flash Point -26°C 49°C

2. Key Applications

2.1 Pharmaceutical Synthesis

• Intermediate for fluorinated APIs including antibiotics (e.g., ciprofloxacin derivatives)
• Peptide modification through amino group protection

2.2 Specialty Chemicals

• Production of fluorinated surfactants with enhanced thermal stability (up to 300°C)
• Synthesis of liquid crystal compounds for display technologies

3. Operational Guidelines

3.1 Safety Protocols

• Mandatory PPE: Chemically resistant gloves (≥0.4mm Viton®), full-face respirator with acid gas cartridges
• Storage: Maintain under dry nitrogen atmosphere at 2-8°C in amber glass containers

3.2 Reactivity Profile

• Hydrolysis rate: 98% decomposition within 15min at 25°C (pH 7)
• Incompatible with: Primary amines, strong oxidizers, alkaline materials

4. Industry Use Cases

  • Electronics Manufacturing: Surface activation of polymer substrates for microchip packaging
  • Agrochemicals: Synthesis of weather-resistant fluorinated pesticides

5. Customer Success Stories

Case 1: Shanghai PharmaTech Co., Ltd.

• Application: Synthesis of third-generation quinolone antibiotics
• Result: 22% yield improvement vs. traditional acetylation methods

Case 2: Advanced Materials Inc. (USA)

• Application: Production of fuel cell proton exchange membranes
• Outcome: Achieved 15% higher proton conductivity at 80°C

6. Contact for Technical Consultation

Email: info@vivalr.com
Tel: (86) 15866781826
Available: Mon-Fri 8:00-17:00 CST

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