3,5-Difluorophenylboronic acid Cas 156545-07-2

3,5-Difluorophenylboronic Acid (CAS 156545-07-2): Comprehensive User Guide

Table of Contents

• 1. Product Overview & Specifications
• 2. Key Applications & Use Cases
• 3. Performance in Suzuki-Miyaura Cross-Coupling
• 4. Pharmaceutical Intermediate Case Studies
• 5. Client Success Stories
• 6. Request Customized Solutions

1. Product Overview & Specifications

2. Key Applications & Use Cases

2.1 Suzuki-Miyaura Cross-Coupling

Enables synthesis of biaryl compounds with fluorine substituents for advanced material development.

2.2 Pharmaceutical Intermediates

Critical building block for kinase inhibitors and CNS-targeting drug candidates.

2.3 OLED Materials

Used in electron-transport layers for improved device efficiency.

3. Suzuki Reaction Optimization

4. Pharmaceutical Case Studies

4.1 JAK Inhibitor Development

Used in intermediate synthesis for selective Janus kinase inhibitors currently in Phase II trials.

4.2 PET Tracer Synthesis

Key precursor in fluorine-18 labeled diagnostic agents for neurological imaging.

5. Verified Client Implementations

5.1 WuXi AppTec (2023)

Scale-up to 50kg batch size for anticoagulant drug intermediate production.

5.2 Merck KGaA (2024)

Adopted in high-throughput screening library for oncology target identification.

5.3 University of Cambridge (2024)

Utilized in asymmetric synthesis research for chiral fluorinated compounds.

6. Technical & Commercial Inquiry

Contact our boron chemistry specialists:

Email: info@vivalr.com

Tel: (86) 15866781826

Request:

• Custom purity specifications (98-99.9%)
• Bulk pricing (100g-100kg quantities)
• Technical packages (COA, MSDS, NMR)