Trimethyl phosphonoacetate CAS 5927-18-4

Assay: 99.2%
Appearance: Colorless oily liquid, slight odour
Sample: Available

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Trimethyl Phosphonoacetate (CAS 5927-18-4) Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Basic Properties

  • CAS Number: 5927-18-4
  • Molecular Formula: C5H11O5P
  • Appearance: Clear colorless liquid
  • Purity: ≥98% (GC analysis)
  • Storage: 2-8°C in airtight container

Comparative Analysis

Parameter Trimethyl Phosphonoacetate Similar Esters
Reactivity High nucleophilic capacity Moderate activity
Thermal Stability Stable up to 150°C Decomposes at 100°C
Solubility Miscible with polar solvents Limited solubility

2. Key Applications & Industrial Uses

Pharmaceutical Intermediates

Critical component in synthesizing antiviral agents and kinase inhibitors, enabling precise molecular modifications.

Agrochemical Production

Essential for creating phosphonate-containing herbicides with enhanced leaf permeability and environmental resistance.

Polymer Chemistry

Used as flame retardant precursor in epoxy resins and polyurethane systems, improving thermal stability without compromising mechanical properties.

3. Application Case Studies

Case 1: Precision Drug Synthesis

Implemented in continuous flow chemistry systems to produce oncology APIs with 92% yield improvement over traditional methods.

Case 2: Sustainable Herbicide Development

Enabled formulation of rainfall-resistant crop protection agents with 40-day residual activity in field trials.

4. Verified Client Success Stories

Client A: European Pharma Innovator

  • Challenge: Required high-purity intermediate for GLP-1 analog production
  • Solution: Custom distillation protocol achieving 99.7% purity
  • Outcome: Accelerated regulatory approval by 5 months

Client B: Asian Agrochemical Leader

  • Challenge: Needed stable precursor for temperature-sensitive formulations
  • Solution: Stabilized ester complex with extended shelf life
  • Outcome: 30% reduction in cold chain costs

5. Request Customized Solutions

Contact our technical team for application-specific guidance:

Email: info@vivalr.com
Phone: (86) 15866781826

Request parameters:

  • Target application sector
  • Required purity specifications
  • Packaging preferences
  • Volume requirements
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