Thymolphthalein (CAS 125-20-2) Comprehensive User Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Thymolphthalein (CAS 125-20-2) | Industry Standard Indicators |
|---|---|---|
| Molecular Formula | C28H30O4 | C28H30O4 |
| Molecular Weight | 430.54 g/mol | 430.54 g/mol |
| pH Transition Range | 9.3–10.5 (colorless ⇌ blue) | 9.0–10.5 (typical for phenolic indicators) |
| Melting Point | 248–254°C | 245–255°C |
| Solubility | Ethanol, acetone, sulfuric acid, alkaline solutions; insoluble in water | Ethanol-based solvents preferred |
| Purity Grade | 98–99% (varies by supplier) | ≥95% (analytical grade) |
2. Functional Applications
Thymolphthalein serves as a high-precision acid-base indicator with critical roles in:
- Titration Analysis: Detects endpoints in alkaline titrations (e.g., hydroxides, carbonates).
- Educational Laboratories: Visual demonstration of pH transitions in chemical reactions.
- Industrial Quality Control: Monitors pH in pharmaceutical synthesis and chemical manufacturing.
- Specialized Formulations: Combined with other indicators to narrow transition ranges for enhanced precision.
3. Implementation Scenarios
Scenario 1: Hydroxide Titration
A 0.1% ethanolic solution of thymolphthalein is used to determine the equivalence point in sodium hydroxide (NaOH) standardization against potassium hydrogen phthalate. The color shift from colorless to blue occurs sharply at pH 10.0.
Scenario 2: Carbonate Analysis
In water treatment facilities, thymolphthalein aids in distinguishing between carbonate and bicarbonate alkalinity when paired with phenolphthalein, enabling accurate calculation of CO32− concentrations.
4. Client Case Studies
Case Study A: Pharmaceutical R&D Laboratory
A leading pharmaceutical company utilized thymolphthalein (99% purity) to optimize the synthesis of alkaline-sensitive APIs. The indicator provided reproducible endpoints in amine titration, reducing process variability by 18%.
Case Study B: Chemical Manufacturer
A specialty chemical producer integrated thymolphthalein into their QC protocol for surfactant production, achieving ISO 9001 compliance through improved batch-to-batch pH consistency.
5. Contact for Technical Inquiry
For product specifications, bulk orders, or technical support:
Email: info@vivalr.com
Tel: (86) 15866781826
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