Dimethyl sulfate CAS 77-78-1

Chemical Name:Dimethyl sulfate
Appearance: Transparent oily liquid
Assay: 99%min
Packing: 250kg/drum
Capacity: 5000MT/year
Sample: Available

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Dimethyl Sulfate (CAS 77-78-1) User Guide

Table of Contents

Product Information & Specifications

Parameter Dimethyl Sulfate Diethyl Sulfate Methyl Iodide
CAS Number 77-78-1 64-67-5 74-88-4
Molecular Formula C2H6O4S C4H10O4S CH3I
Boiling Point 188°C (dec) 209°C 42°C
Reactivity High methylating agent Moderate ethylating agent Rapid alkylation
Toxicity Extremely toxic (T+) Harmful (Xn) Toxic (T)

Detailed Applications

Primary Industrial Uses:

  • Methylation agent in pharmaceutical intermediates
  • Dye manufacturing catalyst
  • Quaternary ammonium compound production
  • Surface treatment chemicals
  • Laboratory-scale organic synthesis

Operational Guidelines

Critical Safety Protocols:

  1. Use NIOSH-approved respirators with organic vapor cartridges
  2. Maintain operating temperatures below 40°C
  3. Implement secondary containment for storage vessels
  4. Neutralize spills with 10% ammonia solution immediately

Industry Use Cases

Pharmaceutical Application:
Production of antihistamine APIs through O-methylation reactions, achieving 92% yield improvement over traditional methods.

Agrochemical Implementation:
Synthesis of pyrethroid insecticides with 40% reduced reaction time compared to ethylating alternatives.

Client Success Stories

Case 1: European Pharma Innovator
Challenge: Required high-purity methylated intermediates for antiviral drug development
Solution: Optimized dimethyl sulfate stoichiometry in nucleoside methylation
Outcome: Achieved 99.8% purity with 30% cost reduction

Case 2: Asian Dye Manufacturer
Challenge: Inconsistent color fastness in textile dyes
Solution: Implemented controlled dimethyl sulfate methylation process
Outcome: Produced wash-fast dyes meeting REACH compliance standards

Technical Consultation & Ordering

For material safety data sheets or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Our chemical engineering team provides:

  • Custom concentration formulations
  • Reaction optimization studies
  • Closed-system handling solutions
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