D(+)-Trehalose Dihydrate (CAS 6138-23-4): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
D(+)-Trehalose Dihydrate (CAS 6138-23-4) is a non-reducing disaccharide widely used in pharmaceuticals, food preservation, and biotechnology. Its unique stability under extreme conditions makes it ideal for lyophilization, enzyme stabilization, and cryoprotection.
Technical Specifications
| Parameter | D(+)-Trehalose Dihydrate | Competitor A (Sucrose) | Competitor B (Maltose) |
|---|---|---|---|
| Molecular Formula | C₁₂H₂₂O₁₁·2H₂O | C₁₂H₂₂O₁₁ | C₁₂H₂₂O₁₁ |
| Water Activity | 0.3-0.5 | 0.6-0.8 | 0.7-0.9 |
| Thermal Stability | Up to 120°C | Decomposes at 80°C | Decomposes at 75°C |
2. Key Applications & Industrial Uses
Pharmaceutical Industry
Used as a lyoprotectant in vaccine formulations and antibody storage solutions, maintaining biomolecule integrity during freeze-drying.
Food Technology
Extends shelf life in baked goods and dairy products by reducing starch retrogradation and lipid oxidation.
Cosmetics
Enhances moisturization in skincare products through its hygroscopic properties and cell membrane stabilization.
3. Detailed Usage Scenarios
Case 1: Lyophilized Vaccine Production
Step 1: Prepare 10% (w/v) trehalose solution in PBS buffer
Step 2: Mix with antigen solution at 1:1 ratio
Step 3: Freeze-dry at -50°C under 0.1 mBar vacuum
Result: 98% antigen recovery rate after 24-month storage
4. Client Success Stories
| Client | Application | Outcome |
|---|---|---|
| BioPharm Solutions Ltd. (UK) | mRNA Vaccine Stabilization | Achieved 36-month stability at 4°C |
| NutriFoods Inc. (USA) | Gluten-Free Bakery Products | Extended freshness from 3 to 14 days |
| DermaCare AG (Germany) | Anti-Aging Cream Formulation | 30% improvement in skin hydration metrics |
5. Request a Quote
Contact our technical team for batch-specific COA or formulation support:
Email: info@vivalr.com
Tel: (86) 15866781826
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