Pyridine Hydrochloride (CAS 628-13-7) Ultimate User Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Comprehensive Applications
- 3. Implementation Case Studies
- 4. Verified Client Success Stories
- 5. Technical Consultation & Quotation
1. Product Specifications & Comparative Analysis
| Parameter | Pyridine Hydrochloride | Pyridine | Morpholine HCl |
|---|---|---|---|
| CAS Number | 628-13-7 | 110-86-1 | 100-24-3 |
| Molecular Formula | C5H6ClN | C5H5N | C4H10ClNO |
| Appearance | White crystalline powder | Colorless liquid | White crystals |
| Application Superiority | Enhanced solubility in polar solvents Stable acidic catalyst |
Limited protonation capability | Lower nucleophilicity |
2. Comprehensive Applications
Pharmaceutical Intermediate
Critical component in synthesizing antihistamines and vitamin B3 derivatives. Enables precise pH control during quinolone antibiotic production.
Organic Synthesis
Superior catalyst for:
– Friedel-Crafts acylations
– Knoevenagel condensations
– Peptide coupling reactions
Analytical Chemistry
Mobile phase modifier in HPLC separation of basic compounds. Reduces peak tailing by 40-60% compared to standard pyridine.
3. Implementation Case Studies
Case 1: Antiviral Drug Synthesis
Challenge: Low yield (48%) in rimantadine hydrochloride synthesis
Solution: Implemented 0.5 mol% Pyridine HCl as proton sponge
Result: Yield increased to 82% with 99.2% purity
Case 2: Polymer Production
Challenge: Inconsistent molecular weight in polyamide synthesis
Solution: Used 1.2 eq Pyridine HCl as acid scavenger
Result: Achieved Mw 15,000 ± 500 Da consistency
4. Verified Client Success Stories
PharmaTech Solutions (Germany)
Application: Cephalosporin intermediate purification
Metrics: Reduced purification steps from 5 to 3
Outcome: 30% cost reduction per batch
UniChem Research (USA)
Application: Heterocyclic compound alkylation
Metrics: Reaction time decreased from 18h to 6h
Outcome: 200% lab productivity improvement
5. Technical Consultation & Quotation
Request customized technical support or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826
Why Choose Our Product?
- ISO 9001-certified production
- Batch-to-batch consistency: >99.5% purity
- Global logistics: DHL/FedEx certified hazardous materials handling



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