Meglumine (CAS 6284-40-8): Comprehensive User Guide
Table of Contents
1. Product Overview & Specifications
Meglumine (CAS 6284-40-8), chemically known as 1-Deoxy-1-(methylamino)-D-glucitol, is a hydrophilic organic compound widely used in pharmaceutical formulations.
| Parameter | Meglumine | Comparable Compounds |
|---|---|---|
| Molecular Formula | C7H17NO5 | Glucamine, Mannitol |
| Purity | ≥99% | 95-98% (typical alternatives) |
| Solubility | Highly water-soluble (650 g/L at 20°C) | Variable solubility in alternatives |
| Storage | 2-8°C in airtight container | Room temperature (some alternatives) |
2. Key Applications of Meglumine
Pharmaceutical Uses:
- Contrast agent formulations (e.g., meglumine diatrizoate)
- Drug solubilization enhancer
- Stabilizer in injectable solutions
Industrial Applications:
- Chemical synthesis intermediate
- Biotechnology research applications
3. Usage Guidelines & Best Practices
Handling Procedures:
- Use PPE during handling
- Maintain pH between 6.5-7.5 in formulations
- Avoid prolonged exposure to temperatures >40°C
Formulation Tips:
- Optimal concentration: 10-30% w/v in contrast media
- Combine with sodium salts for ionic balance
4. Industry Application Cases
Medical Imaging:
Used in 78% of iodinated contrast agents for CT scans, improving patient tolerance by reducing osmotic load.
Drug Development:
Enhanced solubility of poorly water-soluble APIs by 40-60% in recent preclinical trials.
5. Client Success Stories
Case 1: European Pharma Manufacturer
Challenge: Needed stable formulation for high-concentration contrast media
Solution: Customized meglumine-based formulation achieving 12-month stability
Result: 30% production cost reduction
Case 2: Asian Research Institute
Challenge: Required low-osmolality agent for animal studies
Solution: Optimized meglumine-sodium ratio (3:1)
Result: Improved study accuracy by 25%
6. Request Customized Solutions
Our technical team specializes in developing tailored meglumine formulations for:
- Contrast media optimization
- Novel drug delivery systems
- Specialty chemical synthesis
Contact Our Experts:
Email: info@vivalr.com
Phone: (86) 15866781826



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