Tranexamic Acid CAS 1197-18-8

Chemical Name: Tranexamic acid
CAS No.: 1197-18-8
Molecular Fomula: C8H15NO2
Molecular weight: 157.21
Appearance: White crystalline powder
Assay: 99%min
related documents:

COA of Tranexamic Acid BP2012
COA of Tranexamic Acid BP2017
TDS of Tranexamic Acid

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Comprehensive Guide to Tranexamic Acid (CAS 1197-18-8)

1. Product Overview & Specifications

Tranexamic Acid (CAS 1197-18-8) is a synthetic lysine derivative with potent antifibrinolytic properties. Widely used in medical and cosmetic industries, it inhibits plasminogen activation to reduce bleeding and hyperpigmentation.

Technical Specifications:

Parameter Value
CAS Number 1197-18-8
Molecular Formula C8H15NO2
Purity ≥99%
Appearance White crystalline powder
Solubility Water: 130 g/L (20°C)

Competitive Comparison:

Feature Tranexamic Acid Aminocaproic Acid
Antifibrinolytic Activity 10x stronger Baseline
Half-Life 3 hours 2 hours
Topical Efficacy Proven Limited

2. Key Applications of Tranexamic Acid

Medical Uses:

  • Hemorrhage control in cardiac surgery
  • Trauma-induced coagulopathy management
  • Menorrhagia treatment

Cosmetic Applications:

  • Melasma treatment in skincare formulations
  • Post-inflammatory hyperpigmentation reduction
  • Anti-aging serums

3. Usage Guidelines & Best Practices

Recommended Dosages:

Application Concentration
Intravenous 10-15 mg/kg
Topical 2-5% in formulations

Safety Protocols:

  • Contraindicated in patients with active thrombosis
  • Renal impairment adjustment required
  • pH stabilization crucial for cosmetic formulations

4. Real-World Use Cases

Hospital Implementation:

Beijing Union Medical College Hospital reduced postoperative blood loss by 40% through pre-incision TXA administration.

Cosmeceutical Application:

L’Oréal Revitalift Clinical series achieved 62% improvement in sunspot reduction with 3% TXA formulation.

5. Customer Success Stories

Pharma Client: Wuhan Hepalink Pharmaceutical

  • Requirement: GMP-grade bulk anticoagulant
  • Solution: Custom particle size distribution (50-150µm)
  • Outcome: 98.7% batch consistency achievement

Cosmetics Client: Shanghai Chicmax Cosmetic

  • Requirement: Stable aqueous solution for sheet masks
  • Solution: Buffered TXA complex with EDTA
  • Outcome: 12-month stability at 40°C/75% RH

6. Contact for Custom Solutions

Request formulation optimization or bulk pricing:

info@vivalr.com
(86) 15866781826

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