trimethylacetic anhydride cas 1538-75-6
Chemical Name: Trimethylacetic anhydride
CAS No.:1538-75-6
Molecular Fomula: C10H18O3
Molecular weight: 186.25
Appearance: Colorlesstransparentliquid
Assay:99.0%min
related documents:
COA of trimethylacetic anhydride
TDS of trimethylacetic anhydride
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Trimethylacetic Anhydride (CAS 1538-75-6) Comprehensive Guide
Table of Contents
- Product Overview & Specifications
- Key Applications
- Industry Use Cases
- Supplier Profiles
- Contact for Quotation
Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 1538-75-6 |
| Molecular Formula | C10H18O3 |
| Molecular Weight | 186.25 g/mol |
| Boiling Point | 193°C (lit.) |
| Density | 0.918 g/mL at 25°C |
| Refractive Index | n20/D: 1.409 |
| Flash Point | 57.2°C (135°F) |
| Solubility | Miscible with acetonitrile |
Comparative Analysis
Trimethylacetic anhydride exhibits superior thermal stability compared to similar aliphatic anhydrides, with a flash point 20% higher than isobutyric anhydride (CAS 97-72-3), making it safer for high-temperature applications.
Key Applications
Industrial Uses
- Pharmaceutical Intermediates: Acetylation agent for antibiotic synthesis
- Polymer Chemistry: Modifier for polyester resins
- Agrochemicals: Precursor in herbicide formulations
Functional Advantages
- Enables controlled acylation reactions
- Enhances product stability in polymer crosslinking
- Improves reaction yields in sterically hindered syntheses
Industry Use Cases
Case Study 1: Pharmaceutical Synthesis
A European API manufacturer achieved 92% yield improvement in cephalosporin intermediate production by implementing trimethylacetic anhydride as the acylating agent, reducing reaction time from 18 to 8 hours.
Case Study 2: Specialty Coatings
Japanese polymer researchers developed UV-resistant automotive coatings using trimethylacetic anhydride-modified alkyd resins, demonstrating 40% longer weatherability in accelerated aging tests.
Supplier Profiles
| Supplier | Specifications | Pricing | Contact |
|---|---|---|---|
| Hubei Dahao Chemical | 99% purity, 1kg-25kg packaging | $100-$2,500/unit | Ms. Liu: +86 13986246535 |
| Hubei Jusheng Tech | Pharma-grade, ISO-certified | Custom quotes | Ms. Wang: +86 18871490354 |
| Hubei Shixing Chemical | Bulk quantities (≥1000kg) | $100/kg (volume discounts) | Mr. Jiang: +86 18086426449 |
Contact for Quotation
Request custom formulations or bulk pricing:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Technical support available for formulation optimization and regulatory compliance guidance.



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