liquid sodium ethoxide cas 141-52-6

Chemical Name: Liquid sodium ethylate
CAS No.: 141-52-6
Chemicalformula:C2H5NaO
MolecularWeight:68.06

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Product Overview: Liquid Sodium Ethoxide (CAS 141-52-6)

Liquid Sodium Ethoxide (CAS 141-52-6), also known as sodium ethanolate, is a highly reactive alkaline compound widely used in organic synthesis. It is typically supplied as a clear, colorless to yellowish solution in ethanol (20-30% concentration) for industrial applications.

Chemical Properties

Property Value
CAS Number 141-52-6
Molecular Formula C₂H₅ONa
Molecular Weight 68.05 g/mol
Density 0.868 g/cm³ (21% in ethanol)
Boiling Point 78°C (ethanol solvent)
pH >14 (strongly alkaline)

Key Parameters & Comparison

Parameter Liquid Form Solid Form
Reactivity High (immediate activation) Requires dissolution
Handling Safety Controlled in solution Dust explosion risk
Storage 2-8°C under inert gas Room temperature (dry)
Typical Concentration 21-30% in ethanol ≥95% purity

Detailed Applications

1. Pharmaceutical Synthesis

Used as catalyst in:

  • Beta-lactam antibiotic production
  • Steroid derivatization
  • Peptide bond formation

2. Biodiesel Production

Key catalyst for transesterification:

  • Converts triglycerides to methyl esters
  • Optimal reaction temperature: 60-70°C
  • Typical dosage: 0.5-1.5% of oil weight

3. Polymer Chemistry

  • Initiation of ethylene oxide polymerization
  • Production of polyether polyols

Usage Guidelines

Safety Measures

Aspect Requirement
Storage Nitrogen atmosphere, stainless steel containers
PPE Chemical goggles, neoprene gloves, face shield
Spill Management Neutralize with weak acid (e.g., diluted acetic acid)

Reaction Optimization

  • Maintain moisture content <0.1%
  • Ethanol content adjustment for viscosity control

Case Studies

Case 1: Pharmaceutical Intermediate Synthesis

Client: European API Manufacturer

  • Challenge: Low yield (58%) in alkylation step
  • Solution: Optimized sodium ethoxide concentration to 2.7 mol%
  • Result: Yield increased to 89%, reaction time reduced by 40%

Case 2: Biodiesel Plant Optimization

Client: Southeast Asian Biofuel Producer

  • Issue: Catalyst consumption 1.8% of feedstock
  • Improvement: Implemented two-stage catalysis with 21% liquid sodium ethoxide
  • Outcome: Catalyst use reduced to 0.9%, FAME purity 99.2%

Inquiry & Contact

For technical specifications or customized solutions:

Email: info@vivalr.com
Tel: (86) 15866781826

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