Table of Contents
- Product Overview
- Key Parameters & Comparison
- Detailed Applications
- Usage Guidelines
- Case Studies
- Inquiry & Contact
Product Overview: Liquid Sodium Ethoxide (CAS 141-52-6)
Liquid Sodium Ethoxide (CAS 141-52-6), also known as sodium ethanolate, is a highly reactive alkaline compound widely used in organic synthesis. It is typically supplied as a clear, colorless to yellowish solution in ethanol (20-30% concentration) for industrial applications.
Chemical Properties
| Property | Value |
|---|---|
| CAS Number | 141-52-6 |
| Molecular Formula | C₂H₅ONa |
| Molecular Weight | 68.05 g/mol |
| Density | 0.868 g/cm³ (21% in ethanol) |
| Boiling Point | 78°C (ethanol solvent) |
| pH | >14 (strongly alkaline) |
Key Parameters & Comparison
| Parameter | Liquid Form | Solid Form |
|---|---|---|
| Reactivity | High (immediate activation) | Requires dissolution |
| Handling Safety | Controlled in solution | Dust explosion risk |
| Storage | 2-8°C under inert gas | Room temperature (dry) |
| Typical Concentration | 21-30% in ethanol | ≥95% purity |
Detailed Applications
1. Pharmaceutical Synthesis
Used as catalyst in:
- Beta-lactam antibiotic production
- Steroid derivatization
- Peptide bond formation
2. Biodiesel Production
Key catalyst for transesterification:
- Converts triglycerides to methyl esters
- Optimal reaction temperature: 60-70°C
- Typical dosage: 0.5-1.5% of oil weight
3. Polymer Chemistry
- Initiation of ethylene oxide polymerization
- Production of polyether polyols
Usage Guidelines
Safety Measures
| Aspect | Requirement |
|---|---|
| Storage | Nitrogen atmosphere, stainless steel containers |
| PPE | Chemical goggles, neoprene gloves, face shield |
| Spill Management | Neutralize with weak acid (e.g., diluted acetic acid) |
Reaction Optimization
- Maintain moisture content <0.1%
- Ethanol content adjustment for viscosity control
Case Studies
Case 1: Pharmaceutical Intermediate Synthesis
Client: European API Manufacturer
- Challenge: Low yield (58%) in alkylation step
- Solution: Optimized sodium ethoxide concentration to 2.7 mol%
- Result: Yield increased to 89%, reaction time reduced by 40%
Case 2: Biodiesel Plant Optimization
Client: Southeast Asian Biofuel Producer
- Issue: Catalyst consumption 1.8% of feedstock
- Improvement: Implemented two-stage catalysis with 21% liquid sodium ethoxide
- Outcome: Catalyst use reduced to 0.9%, FAME purity 99.2%
Inquiry & Contact
For technical specifications or customized solutions:
Email: info@vivalr.com
Tel: (86) 15866781826



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