4′-Hydroxyacetophenone CAS 99-93-4
Chemical Name: 4′-Hydroxyacetophenone
CAS No.: 99-93-4
Molecular Formula: C8H8O2
Molecular weight: 136.15
Appearance: White crystalline solid
related documents:
COA of 4′-Hydroxyacetophenone
TDS of 4′-Hydroxyacetophenone
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4′-Hydroxyacetophenone (CAS 99-93-4): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
Chemical Name: 4′-Hydroxyacetophenone
CAS Number: 99-93-4
Molecular Formula: C8H8O2
Molecular Weight: 136.15 g/mol
Physical Properties
| Property | Value |
|---|---|
| Appearance | White crystalline powder |
| Melting Point | 107–135°C (lit.) |
| Boiling Point | 147–148°C at 3 mmHg |
| Density | 1.109–1.14 g/cm³ |
| Solubility | 10 g/L in water (22°C), soluble in methanol, ethanol, acetone |
Supplier Comparison
| Supplier | Purity | Packaging |
|---|---|---|
| Supplier A | ≥99% | 25 kg/drum |
| Supplier B | 99.5% | 1–25 kg customizable |
2. Key Applications
- Pharmaceuticals: Intermediate for synthesizing choleretic drugs (e.g., bile acid sequestrants).
- Cosmetics: Preservative in skincare products (FEMA 4330 approved), replacing parabens.
- Organic Synthesis: Building block for fragrances, agrochemicals, and specialty polymers.
- Research: Analytical reference standard in chromatography.
3. Industry Use Cases
Case 1: Preservative in Organic Cosmetics
A European skincare brand uses 4′-Hydroxyacetophenone (0.2–0.5% concentration) as a paraben-free preservative in serums, extending shelf life by 18 months while maintaining pH stability.
Case 2: Drug Intermediate Production
A Chinese pharmaceutical company utilizes this compound in a 5-step synthesis of Ursodeoxycholic Acid (UDCA), achieving 92% yield with 99.8% HPLC purity.
4. Client Success Stories
Client A: Specialty Chemical Manufacturer
Challenge: Required 500 kg/month of 99.9% pure material for high-end fragrance production.
Solution: Customized purification process reduced impurities to <0.1%, enabling ISO 22716 certification.
Client B: Research Institute
Challenge: Needed analytical-grade reference standard with full documentation.
Solution: Supplied batch-tested material with COA, MSDS, and 1H/13C NMR spectra, accelerating their FDA submission timeline by 6 weeks.
5. Request a Quote
Contact our technical sales team for pricing, samples, or custom synthesis inquiries:



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