1. Product Overview & Specifications

BOC-D-4,4′-Biphenylalanine (CAS 128779-47-5) is a protected amino acid derivative widely used in peptide synthesis and pharmaceutical research. Its unique biphenyl structure enhances stability and binding affinity in molecular designs.

2. Applications & Use Cases

Key Applications:

• Peptide Drug Development: Enhances peptide stability in protease-rich environments.
• Kinase Inhibitor Design: Biphenyl moiety improves target binding in oncology research.
• Bioconjugation: Used as a linker in antibody-drug conjugates (ADCs).

Performance Advantages:

• Superior in vivo stability compared to non-aromatic analogs.
• Enables precise stereochemical control in chiral molecule synthesis.

3. Client Success Stories

Case Study 1: Oncology Therapeutics (Shanghai) Co., Ltd.

• Challenge: Improve half-life of PD-1 inhibitor peptide.
• Solution: Incorporated BOC-D-4,4′-Biphenylalanine at N-terminus.
• Result: 3.2x longer serum stability vs. original compound.

Case Study 2: Advanced Materials Research Institute (Singapore)

• Challenge: Develop self-assembling peptides for conductive nanomaterials.
• Solution: Utilized biphenylalanine’s π-π stacking capability.
• Result: Achieved 15nm conductive nanowires with 98% uniformity.

4. Technical Comparison

5. Contact for Custom Solutions

Request bulk pricing, COA, or custom modifications:

• Email: info@vivalr.com
• Tel: (86) 15866781826

Technical Support: Our peptide chemists provide free consultation on:

• SPPS optimization strategies
• Biphenylalanine incorporation techniques
• Analytical method development (HPLC/MS)