(R)-(-)-Epichlorohydrin (CAS 51594-55-9) Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Value |
|---|---|
| CAS Number | 51594-55-9 |
| Molecular Formula | C3H5ClO |
| Molecular Weight | 92.52 g/mol |
| Optical Purity | ≥99.9% enantiomeric excess |
| Appearance | Colorless transparent liquid |
2. Key Applications
- Chiral Intermediate Synthesis: Critical component in production of enantiomerically pure pharmaceuticals
- Pharmaceutical Manufacturing: Precursor for β-blockers, antihypertensive drugs, and antidepressants
- Agrochemicals: Building block for chiral pesticides and herbicides
- Advanced Materials: Used in epoxy resin modification and specialty polymers
3. Physical & Chemical Properties
| Property | Value |
|---|---|
| Boiling Point | 116°C |
| Melting Point | -48°C |
| Refractive Index | n20/D 1.43 |
| Flash Point | 32°C (89.6°F) |
| Water Solubility | Immiscible |
4. Industrial Use Cases
Case 1: Antihypertensive Drug Synthesis
Used as chiral building block in multi-step synthesis of (S)-Metoprolol, achieving >99.5% enantiomeric purity in final API.
Case 2: Specialty Epoxy Production
Key component in manufacturing optically active epoxy resins for aerospace composite materials.
5. Supplier Information
| Supplier | Packaging | Specifications |
|---|---|---|
| Hubei Shengbailai Bio-Tech | 230kg/drum | Purity ≥99.9%, Storage: RT, sealed |
| Shanghai Leyan | 25g/100g | HPLC ≥98%, Storage: -20°C |
6. Safety & Handling
- Use chemical-resistant gloves and eye protection
- Store in sealed containers under inert atmosphere
- Handle in well-ventilated areas (PEL 5ppm)
- Follow GHS hazard statements: H226, H301, H311, H314, H317
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