5-Amino-2,4-Difluorophenol (CAS 113512-71-3): Comprehensive Product Guide
Table of Contents
- 1. Product Specifications & Comparative Analysis
- 2. Industrial Applications & Functional Advantages
- 3. Operational Protocols & Safety Guidelines
- 4. Case Study: Pharmaceutical Intermediate Synthesis
- 5. Case Study: Agrochemical Formulation Development
- 6. Technical Inquiry & Procurement Process
1. Product Specifications & Comparative Analysis
| Parameter | 5-Amino-2,4-Difluorophenol | 2,4-Difluorophenol | 5-Nitro-2,4-difluorophenol |
|---|---|---|---|
| CAS Number | 113512-71-3 | 2713-30-8 | 113512-70-2 |
| Molecular Formula | C6H5F2NO | C6H4F2O | C6H3F2NO3 |
| Purity Grade | ≥99% (HPLC) | ≥98% | ≥97% |
| Reactivity Index | High (amine group) | Moderate | Low (nitro group) |
2. Industrial Applications & Functional Advantages
2.1 Pharmaceutical Intermediate
Critical component in synthesis of:
- EGFR tyrosine kinase inhibitors
- Anticancer drug candidates
- Antimicrobial agents
2.2 Agrochemical Applications
Key precursor for:
- Fluorinated pesticide development
- Herbicide metabolites
- Fungicidal compounds
3. Operational Protocols & Safety Guidelines
3.1 Handling Procedures
- Storage: 2-8°C in amber glass under nitrogen
- Solubility: 28 mg/mL in DMSO at 25°C
3.2 Reaction Optimization
- Optimal coupling conditions: 80°C in DMF with DIEA
- Typical yield: 72-85% in Buchwald-Hartwig amination
4. Case Study: Pharmaceutical Intermediate Synthesis
Client Profile
European Oncology Research Consortium
Application
Synthesis of third-generation ALK inhibitors
Results
- Improved reaction efficiency by 40% vs. non-fluorinated analogs
- Achieved 99.2% chiral purity
5. Case Study: Agrochemical Formulation Development
Client Profile
Global Crop Protection Manufacturer
Application
Development of systemic fungicide
Results
- Enhanced soil persistence by 3.2x
- Reduced phytotoxicity by 27%
6. Technical Inquiry & Procurement Process
Quality Assurance
- Batch-specific COA available
- Custom synthesis up to 50kg scale
Contact Information
Technical Support: info@vivalr.com
Phone: (86) 15866781826
Order Specifications
| Package Size | Lead Time | Shipping |
|---|---|---|
| 1g-100g | 3-5 days | Global Express |
| 500g-5kg | 2 weeks | DGR Certified |



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