5-AMINO-2,4-DIFLUOROPHENOL CAS 113512-71-3

Chemical Name: 5-AMINO-2,4-DIFLUOROPHENOL
CAS No.: 113512-71-3
Molecular Fomula: C6H5F2NO
Molecular weight: 145.11
Appearance: Brown powder

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5-Amino-2,4-Difluorophenol (CAS 113512-71-3): Comprehensive Product Guide

Table of Contents

1. Product Specifications & Comparative Analysis

Parameter 5-Amino-2,4-Difluorophenol 2,4-Difluorophenol 5-Nitro-2,4-difluorophenol
CAS Number 113512-71-3 2713-30-8 113512-70-2
Molecular Formula C6H5F2NO C6H4F2O C6H3F2NO3
Purity Grade ≥99% (HPLC) ≥98% ≥97%
Reactivity Index High (amine group) Moderate Low (nitro group)

2. Industrial Applications & Functional Advantages

2.1 Pharmaceutical Intermediate

Critical component in synthesis of:

  • EGFR tyrosine kinase inhibitors
  • Anticancer drug candidates
  • Antimicrobial agents

2.2 Agrochemical Applications

Key precursor for:

  • Fluorinated pesticide development
  • Herbicide metabolites
  • Fungicidal compounds

3. Operational Protocols & Safety Guidelines

3.1 Handling Procedures

  • Storage: 2-8°C in amber glass under nitrogen
  • Solubility: 28 mg/mL in DMSO at 25°C

3.2 Reaction Optimization

  • Optimal coupling conditions: 80°C in DMF with DIEA
  • Typical yield: 72-85% in Buchwald-Hartwig amination

4. Case Study: Pharmaceutical Intermediate Synthesis

Client Profile

European Oncology Research Consortium

Application

Synthesis of third-generation ALK inhibitors

Results

  • Improved reaction efficiency by 40% vs. non-fluorinated analogs
  • Achieved 99.2% chiral purity

5. Case Study: Agrochemical Formulation Development

Client Profile

Global Crop Protection Manufacturer

Application

Development of systemic fungicide

Results

  • Enhanced soil persistence by 3.2x
  • Reduced phytotoxicity by 27%

6. Technical Inquiry & Procurement Process

Quality Assurance

  • Batch-specific COA available
  • Custom synthesis up to 50kg scale

Contact Information

Technical Support: info@vivalr.com
Phone: (86) 15866781826

Order Specifications

Package Size Lead Time Shipping
1g-100g 3-5 days Global Express
500g-5kg 2 weeks DGR Certified
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