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Isotretinoin CAS 4759-48-2 Overview
Basic Specifications
| Parameter | Detail |
|---|---|
| Chemical Name | 13-cis-Retinoic Acid |
| CAS Number | 4759-48-2 |
| Molecular Formula | C20H28O2 |
| Purity | ≥98% (HPLC) |
| Appearance | Yellow crystalline powder |
Specification Comparison
| Vendor | Purity | Package | Storage |
|---|---|---|---|
| Vivalr Chem | 99.2% | 1kg/aluminum foil | 2-8°C |
| Vendor B | 97.8% | 500g/plastic bottle | Room temperature |
Key Applications
Medical Applications
1. Severe nodular acne treatment
2. Chemoprevention agent in high-risk patients
3. Research in dermatological malignancies
Research Applications
• Apoptosis studies
• Retinoid receptor modulation research
• Lipid metabolism investigations
Usage Guidelines
Dosage Information
| Application | Recommended Dose |
|---|---|
| Acne Treatment | 0.5-1.0 mg/kg/day |
| Research Use | 10-100 μM concentrations |
Safety Precautions
⚠️ Teratogenic effects
⚠️ Monitor liver function
⚠️ Contraindicated in pregnancy
Client Success Stories
Case 1: Pharmaceutical Manufacturer
| Client | EuroDerm Solutions |
|---|---|
| Challenge | Stable formulation development |
| Solution | Custom micronization process |
| Result | 30% bioavailability improvement |
Case 2: Research Institute
| Client | Singapore Skin Research Centre |
|---|---|
| Challenge | Compound degradation during trials |
| Solution | Nitrogen-packed packaging |
| Result | 98% stability over 12 months |
Request Custom Quotation
Email: info@vivalr.com
Tel: (86) 15866781826
Technical Support Available:
• Batch-specific COA
• Regulatory documentation
• Stability data packages
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