Isotretinoin CAS 4759-48-2

Chemical Name: Isotretinoin
Synonyms: 13-Cis-Retinoic acid
CAS: 4759-48-2
Molecular Fomula: C20H28O2
Molecular Weight: 300.44
Appearance: Orange or orange crystalline powder
Purity: 99%

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Isotretinoin CAS 4759-48-2 Overview

Basic Specifications

Parameter	Detail
Chemical Name	13-cis-Retinoic Acid
CAS Number	4759-48-2
Molecular Formula	C20H28O2
Purity	≥98% (HPLC)
Appearance	Yellow crystalline powder

Specification Comparison

Vendor	Purity	Package	Storage
Vivalr Chem	99.2%	1kg/aluminum foil	2-8°C
Vendor B	97.8%	500g/plastic bottle	Room temperature

Key Applications

Medical Applications

1. Severe nodular acne treatment
2. Chemoprevention agent in high-risk patients
3. Research in dermatological malignancies

Research Applications

• Apoptosis studies
• Retinoid receptor modulation research
• Lipid metabolism investigations

Usage Guidelines

Dosage Information

Application	Recommended Dose
Acne Treatment	0.5-1.0 mg/kg/day
Research Use	10-100 μM concentrations

Safety Precautions

⚠️ Teratogenic effects
⚠️ Monitor liver function
⚠️ Contraindicated in pregnancy

Client Success Stories

Case 1: Pharmaceutical Manufacturer

Client	EuroDerm Solutions
Challenge	Stable formulation development
Solution	Custom micronization process
Result	30% bioavailability improvement

Case 2: Research Institute

Client	Singapore Skin Research Centre
Challenge	Compound degradation during trials
Solution	Nitrogen-packed packaging
Result	98% stability over 12 months

Request Custom Quotation

Email: info@vivalr.com
Tel: (86) 15866781826

Technical Support Available:
• Batch-specific COA
• Regulatory documentation
• Stability data packages

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