Comprehensive Guide to 4,4′-Bipyridine (CAS 553-26-4)
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications of 4,4′-Bipyridine
- 3. Usage Guidelines
- 4. Comparative Analysis with Similar Compounds
- 5. Industry Case Studies
- 6. How to Purchase or Request a Quote
1. Product Overview & Specifications
4,4′-Bipyridine (CAS 553-26-4) is a bipyridine compound consisting of two pyridine rings connected at the 4-positions. It serves as a versatile ligand in coordination chemistry and material science.
| Parameter | Specification |
|---|---|
| CAS Number | 553-26-4 |
| Molecular Formula | C₁₀H₈N₂ |
| Molecular Weight | 156.18 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in ethanol, DMF, DMSO; slightly soluble in water |
2. Key Applications of 4,4′-Bipyridine
- Coordination Chemistry: Acts as a bridging ligand for synthesizing metal-organic frameworks (MOFs) and coordination polymers.
- Pharmaceutical Intermediates: Used in the synthesis of antiviral and anticancer agents.
- Catalysis: Facilitates cross-coupling reactions in organic synthesis.
- Electroactive Materials: Key component in redox-active systems for batteries and sensors.
3. Usage Guidelines
- Store in a cool, dry place at 2-8°C under inert gas (e.g., nitrogen).
- Use personal protective equipment (PPE) when handling due to potential toxicity.
- Recommended concentration: 0.1-10 mM in organic solvents for MOF synthesis.
4. Comparative Analysis with Similar Compounds
| Compound | CAS Number | Key Difference |
|---|---|---|
| 2,2′-Bipyridine | 366-18-7 | Stronger metal-binding affinity but less versatile in MOF design |
| 1,2-Bis(4-pyridyl)ethane | 4918-97-6 | Flexible linker with lower thermal stability |
5. Industry Case Studies
Case Study 1: MOF Synthesis for Gas Storage
Client: A European energy research institute
Application: Used 4,4′-bipyridine as a rigid linker to create a high-surface-area MOF for hydrogen storage (capacity: 2.3 wt% at 77 K).
Case Study 2: Anticancer Drug Development
Client: A US-based pharmaceutical company
Application: Employed 4,4′-bipyridine derivatives to synthesize platinum(II) complexes showing IC₅₀ = 1.2 µM against lung cancer cells.
Case Study 3: Redox Flow Battery Optimization
Client: An Asian battery manufacturer
Application: Integrated 4,4′-bipyridine-based electrolytes to achieve 89% energy efficiency over 500 charge-discharge cycles.
6. How to Purchase or Request a Quote
For pricing, bulk orders, or technical support:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Submit your requirements to receive a customized quotation within 24 hours.



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