Cholesterol Cas 57-88-5
Chemical Name:Cholesterol
CAS: 57-88-5
Molecular Fomula:C27H46O
Molecular Weight: 386.65
Appearance: White or similar sheet crystal
Purity: 99.2%
related documents:
COA of Cholesterol cas 57-88-5
TDS of Cholesterol cas 57-88-5
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Cholesterol (CAS 57-88-5): Comprehensive Technical Guide
Table of Contents
1. Chemical and Physical Properties
| Property | Value |
|---|---|
| CAS Number | 57-88-5 |
| Molecular Formula | C27H46O |
| Molecular Weight | 386.65 g/mol |
| Melting Point | 148–150°C |
| Boiling Point | 360°C |
| Solubility | Negligible in water; soluble in organic solvents (e.g., ethanol, chloroform) |
| Storage | 2–8°C (dry, protected from light) |
Purity Grades: Available in technical (95%) and research-grade (≥98%) forms, with custom purity options for specialized applications.
2. Biological Functions and Applications
Key Roles in Biology:
- Cell Membrane Stability: Regulates fluidity and permeability of eukaryotic cell membranes.
- Precursor for Synthesis: Essential for producing steroid hormones (e.g., cortisol, estrogen), vitamin D3, and bile acids.
- Lipid Raft Formation: Facilitates cellular signaling and protein sorting.
Industrial and Research Applications:
- Drug Delivery Systems: Integral component of liposomes and lipid nanoparticles for targeted therapeutics.
- Biomaterials: Used in coatings for medical devices to enhance biocompatibility.
- Diagnostics: Standard reference material for lipid profiling in clinical assays.
- Cosmetics: Stabilizes emulsions in skincare formulations.
3. Industrial and Research Use Cases
Case 1: Liposome Production
Application: Cholesterol is blended with phospholipids (e.g., DOPC, DSPC) to create stable liposomal carriers for mRNA vaccines, achieving >90% encapsulation efficiency.
Case 2: Hormone Synthesis
Application: Serves as the starting material for industrial-scale synthesis of cortisone and testosterone derivatives via enzymatic modification.
4. Client Case Studies
Client A: Xi’an Qiyue Biology
Usage: Procured 500 kg of cholesterol (98% purity) annually for lipid nanoparticle (LNP) production. Achieved 30% reduction in manufacturing costs through optimized formulation protocols.
Client B: Shaanxi Xingbei Aike Biotechnology
Usage: Integrated cholesterol into PEGylated nanocarriers for oncology drug delivery, improving tumor targeting efficiency by 40% in preclinical trials.
Client C: Zhengzhou Alpha Chemical
Usage: Supplies research-grade cholesterol to academic institutions for membrane protein studies, cited in 15+ peer-reviewed publications.
5. Quality Standards and Ordering Information
Quality Assurance:
- HPLC-validated purity (95–99%)
- ISO 9001-certified manufacturing
- Batch-specific COA provided
Packaging Options:
- Research-scale: 1 g to 1 kg (vials or glass bottles)
- Bulk orders: 25 kg drums with desiccant
Contact for Quotation:
Email: info@vivalr.com
Tel: (86) 15866781826



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