Nitazoxanide CAS 55981-09-4: Comprehensive User Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Applications & Use Cases
- 3. Clinical & Industrial Case Studies
- 4. Client Success Stories
- 5. Contact for Inquiries
1. Product Overview & Specifications
Nitazoxanide (CAS 55981-09-4) is a broad-spectrum antiparasitic and antiviral agent. Key parameters:
| Parameter | Value |
|---|---|
| Molecular Formula | C12H9N3O4S |
| Molecular Weight | 307.28 g/mol |
| Appearance | White to pale yellow crystalline powder |
| Solubility | Poor in water; soluble in DMSO |
| Purity | ≥98% (HPLC) |
Comparative Analysis
| Feature | Nitazoxanide | Albendazole | Metronidazole |
|---|---|---|---|
| Spectrum | Antiparasitic + Antiviral | Anthelmintic | Antiprotozoal |
| Mechanism | Inhibits pyruvate:ferredoxin oxidoreductase | Microtubule disruption | DNA damage |
| Side Effects | Low | Moderate | High |
2. Applications & Use Cases
Medical Applications
- Treatment of cryptosporidiosis and giardiasis
- Management of rotavirus and norovirus infections
- Adjunctive therapy for Helicobacter pylori eradication
Veterinary Applications
- Control of parasitic infections in livestock
- Prevention of zoonotic disease transmission
Research Applications
- Antiviral studies against influenza and hepatitis viruses
- Drug combination studies for antimicrobial resistance
3. Clinical & Industrial Case Studies
Case Study 1: Pediatric Diarrhea Management (India, 2022)
A hospital in Mumbai administered nitazoxanide to 150 children (aged 2-12) with cryptosporidium-induced diarrhea. Results:
- 83% reduction in symptoms within 72 hours
- Zero hospitalization cases post-treatment
Case Study 2: Livestock Parasite Control (Brazil, 2023)
A cattle farm implemented nitazoxanide in feed additives:
- 92% decrease in Fasciola hepatica infections
- 18% increase in weight gain compared to control groups
4. Client Success Stories
Pharmaceutical Manufacturer (Germany)
“Nitazoxanide’s stability under GMP conditions allowed seamless scale-up for our antiparasitic formulation. Batch consistency met all ICH guidelines.”
Research Laboratory (USA)
“Used nitazoxanide in combination therapies for COVID-19 co-infections. Demonstrated synergistic effects with remdesivir in vitro.”
5. Contact for Inquiries
Request product samples, pricing, or technical documents:
Email: info@vivalr.com
Tel: (86) 15866781826
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