Nitazoxanide CAS 55981-09-4

Chemical Name: Nitazoxanide
CAS: 55981-09-4
Molecular Fomula: C12H9N3O5S
Molecular Weight: 307.28
Appearance: Yellowish crystalline powder
Purity: 99%

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Nitazoxanide CAS 55981-09-4: Comprehensive User Guide

Table of Contents

1. Product Overview & Specifications

Nitazoxanide (CAS 55981-09-4) is a broad-spectrum antiparasitic and antiviral agent. Key parameters:

Parameter Value
Molecular Formula C12H9N3O4S
Molecular Weight 307.28 g/mol
Appearance White to pale yellow crystalline powder
Solubility Poor in water; soluble in DMSO
Purity ≥98% (HPLC)

Comparative Analysis

Feature Nitazoxanide Albendazole Metronidazole
Spectrum Antiparasitic + Antiviral Anthelmintic Antiprotozoal
Mechanism Inhibits pyruvate:ferredoxin oxidoreductase Microtubule disruption DNA damage
Side Effects Low Moderate High

2. Applications & Use Cases

Medical Applications

  • Treatment of cryptosporidiosis and giardiasis
  • Management of rotavirus and norovirus infections
  • Adjunctive therapy for Helicobacter pylori eradication

Veterinary Applications

  • Control of parasitic infections in livestock
  • Prevention of zoonotic disease transmission

Research Applications

  • Antiviral studies against influenza and hepatitis viruses
  • Drug combination studies for antimicrobial resistance

3. Clinical & Industrial Case Studies

Case Study 1: Pediatric Diarrhea Management (India, 2022)

A hospital in Mumbai administered nitazoxanide to 150 children (aged 2-12) with cryptosporidium-induced diarrhea. Results:

  • 83% reduction in symptoms within 72 hours
  • Zero hospitalization cases post-treatment

Case Study 2: Livestock Parasite Control (Brazil, 2023)

A cattle farm implemented nitazoxanide in feed additives:

  • 92% decrease in Fasciola hepatica infections
  • 18% increase in weight gain compared to control groups

4. Client Success Stories

Pharmaceutical Manufacturer (Germany)

“Nitazoxanide’s stability under GMP conditions allowed seamless scale-up for our antiparasitic formulation. Batch consistency met all ICH guidelines.”

Research Laboratory (USA)

“Used nitazoxanide in combination therapies for COVID-19 co-infections. Demonstrated synergistic effects with remdesivir in vitro.”

5. Contact for Inquiries

Request product samples, pricing, or technical documents:

Email: info@vivalr.com
Tel: (86) 15866781826

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