dicyclohexylcarbodiimide cas 538-75-0

Chemical Name: Dicyclohexylcarbodiimide
CAS: 538-75-0
Molecular Fomula: C13H22N2
Molecular Weight:206.33
Appearance:White crystal or primrose transparent liquid
Purity: 99%

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Dicyclohexylcarbodiimide (DCC) CAS 538-75-0: Comprehensive Product Guide

Table of Contents

1. Product Overview & Specifications

Parameter DCC (CAS 538-75-0)
Chemical Formula C13H22N2
Molecular Weight 206.33 g/mol
Appearance White crystalline solid
Purity Grade ≥99% (HPLC)
Solubility Soluble in THF, DMF, DCM
Storage Conditions 2-8°C in airtight container

2. Key Applications & Use Cases

Primary Functional Roles:

  • Peptide coupling reagent in solid-phase synthesis
  • Dehydration agent for esterification reactions
  • Crosslinking agent for polymer modification
  • Nucleic acid analog synthesis activator

Industry Applications:

  • Pharmaceutical intermediates production
  • Bioconjugation in antibody-drug conjugates
  • Functional material development
  • Academic research catalysis

3. Comparative Analysis with Alternatives

Coupling Agent Reaction Efficiency Byproduct Removal Cost Efficiency
DCC High (85-95%) Requires filtration $$
EDC Moderate (75-85%) Water-soluble $$$
DIC High (80-90%) Easy removal $$$$

4. Industry-Specific Implementation Scenarios

Pharmaceutical Manufacturing:

Used in continuous flow synthesis systems for API production, achieving 92% yield in carbamate formation reactions under inert atmosphere.

Biotech Research:

Enables rapid oligonucleotide synthesis with 3.5-hour reaction cycles in automated synthesizers, reducing reagent waste by 40% compared to traditional methods.

5. Verified Customer Success Stories

Case 1: Leading Pharma Company (2023)

  • Challenge: Low yield (68%) in peptide amidation
  • Solution: Optimized DCC/DMAP catalyst system
  • Result: 89% yield with 98.2% purity

Case 2: University Research Lab (2024)

  • Application: Functional polymer synthesis
  • Process: DCC-mediated crosslinking at 45°C
  • Outcome: Achieved 15% higher thermal stability

6. Contact for Custom Solutions

Request technical specifications or discuss bulk order requirements:

  • Email: info@vivalr.com
  • Phone: (86) 15866781826

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7. Clear conversion pathway

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