N-Hydroxysuccinimide (CAS 6066-82-6) Product Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | N-Hydroxysuccinimide | Alternative Reagent |
|---|---|---|
| CAS Number | 6066-82-6 | N/A |
| Purity Grade | ≥99% (HPLC) | 95-98% |
| Molecular Weight | 115.09 g/mol | Varies |
| Solubility | DMSO, DMF, Aqueous buffers | Limited solubility |
2. Applications in Bioconjugation Chemistry
Primary applications in carbodiimide-mediated crosslinking reactions:
- Antibody-drug conjugate (ADC) development
- Protein immobilization for biosensors
- Peptide synthesis activation
3. Operational Guidelines
Optimal reaction conditions:
- pH range: 4.5-7.5 in aqueous solutions
- Recommended molar ratio (EDC:NHS:COOH): 1:2:1
- Reaction time: 15-120 minutes at RT
4. Case Studies
| Application | Result |
|---|---|
| Collagen functionalization | 92% coupling efficiency |
| Quantum dot labeling | 8:1 payload ratio achieved |
5. Industry Client Implementations
Case 1: Biopharma Solutions Co.
- Challenge: Low yield in trastuzumab-emtansine conjugation
- Solution: Optimized NHS:EDC stoichiometry
- Outcome: 40% yield improvement
Case 2: Diagnostic Innovations Ltd.
- Application: Lateral flow assay development
- Result: 15% sensitivity enhancement
6. Request Product Consultation
Contact our technical specialists:
- Email: info@vivalr.com
- Phone: (86) 15866781826
Request SDS documentation or bulk pricing:
- Available packaging: 1g, 10g, 100g, 1kg
- GMP-grade options available
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