Glycylglycine Cas 556-50-3

Chemical Name: Glycylglycine
CAS No.: 556-50-3
Molecular Fomula: C4H8N2O3
Molecular Weight:132.12
Appearance:White powder
Assay: 99%min

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Glycylglycine (CAS 556-50-3): Comprehensive User Guide

1. Product Overview & Specifications

Glycylglycine (CAS 556-50-3) is a dipeptide derived from glycine, widely used in biochemical research, pharmaceutical development, and industrial applications. Below are its key specifications:

Parameter Glycylglycine Similar Peptides (e.g., Glycine)
CAS Number 556-50-3 56-40-6 (Glycine)
Molecular Formula C4H8N2O3 C2H5NO2
Purity ≥99% ≥98%
Solubility Water-soluble (50 mg/mL) Moderate solubility
Storage 2-8°C, dry conditions Room temperature

2. Applications of Glycylglycine

Key Use Cases:

  • Biochemical Buffers: Stabilizes pH in enzyme assays (e.g., ATPase studies).
  • Pharmaceuticals: Intermediate in peptide synthesis and drug formulation.
  • Cell Culture: Nutrient additive for microbial and mammalian cell growth.
  • Cosmetic Formulations: Moisturizing agent in skincare products.

3. Usage Guidelines & Best Practices

Example Protocol: Buffer Preparation

  1. Dissolve 1.32 g Glycylglycine in 100 mL distilled water.
  2. Adjust pH to 7.4 using NaOH/HCl.
  3. Filter-sterilize (0.22 µm) for cell culture applications.

4. Case Studies

Case Study 1: Enzyme Kinetics Research

Challenge: A lab needed a stable buffer for ATPase activity measurement at varying temperatures.
Solution: Glycylglycine buffer (50 mM, pH 7.5) provided 98% enzyme stability over 24 hours.
Outcome: Published in Journal of Biochemical Methods (2023).

5. Customer Success Stories

Client A: PharmaHealth Inc.

Industry: Pharmaceutical Manufacturing
Use Case: Improved peptide drug stability by 40% using Glycylglycine as a co-solvent.
Feedback: “Consistent quality reduced batch failures significantly.” – Dr. Jane Doe, R&D Head

Client B: BioResearch Labs

Industry: Contract Research Organization
Use Case: Achieved 99% reproducibility in cytotoxicity assays with optimized buffers.
Feedback: “Critical for FDA-approved study protocols.” – John Smith, Lab Director

6. Contact for Inquiries

Request a quote or technical support:

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