Laurocapram (CAS 59227-89-3): Comprehensive Technical Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Specification | Comparison (Oil vs Water-Soluble) |
|---|---|---|
| Chemical Name | 1-Dodecylazacycloheptan-2-one |
Oil-Soluble: Compatible with lipophilic formulations
Water-Soluble: Modified for hydrophilic systems |
| CAS Number | 59227-89-3 | |
| Molecular Formula | C18H35NO | |
| Molecular Weight | 281.48 g/mol | |
| Appearance | Colorless to pale yellow viscous liquid | |
| Density (25°C) | 0.906-0.926 g/cm³ | |
| Refractive Index | 1.470-1.473 |
2. Key Applications
Pharmaceuticals
- Enhances transdermal absorption of APIs in topical formulations (creams, ointments)
- Increases bioavailability by 2-5x in controlled studies
Cosmetics
- Improves skin penetration of active ingredients in serums and anti-aging products
- Recommended dosage: 0.5-2% w/w in final formulation
Agrochemicals
- Enhances foliar absorption of pesticides and growth regulators
- Reduces application frequency by 30% in field trials
3. Usage Guidelines
Compatibility Considerations
| Recommended Combinations | Incompatible Materials |
|---|---|
| Ethanol-based systems Silicon emulsions Polyethylene glycols |
Strong acids Petroleum jelly Paraffin wax |
Quality Control
- Purity test method: GC with SE-30 column (USP/EP compliant)
- Acceptance criteria: ≥97% main peak area
4. Industry Case Studies
Case 1: Topical Analgesic Cream
- Client: Wuhan Yuqing Jiaheng Pharmaceutical
- Challenge: Improve diclofenac sodium penetration through stratum corneum
- Solution: 1.5% Laurocapram added to emulsion base
- Result: 68% reduction in time to therapeutic effect
Case 2: Anti-Aging Serum
- Client: Jiangxi Xinshengya Biotechnology
- Challenge: Enhance retinol absorption without irritation
- Solution: Water-soluble Laurocapram at 0.8% concentration
- Result: 40% improvement in collagen production markers
5. Contact Information
For technical specifications, pricing, or formulation support:
| Contact Method | Details |
|---|---|
| info@vivalr.com | |
| Phone | (86) 15866781826 |
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