1. Product Overview & Specifications

1,3,5-Trimethoxybenzene (CAS 621-23-8), also known as sym-Trimethoxybenzene or phloroglucinol trimethyl ether, is a white crystalline compound with the molecular formula C₉H₁₂O₃ and a molecular weight of 168.19 g/mol.

2. Key Applications

• Pharmaceutical Intermediate: Used in synthesizing vasodilators like buflomedil hydrochloride.
• Analytical Chemistry: Secondary reference standard for quantitative ¹H NMR spectroscopy.
• Fragrance Industry: Key aromatic component in Chinese rose cultivars.
• Organic Synthesis: Precursor for studying photochemical reactions (e.g., 1,2-benzodithienyl sulfoxide deoxygenation).

3. Usage Scenarios

Scenario 1: Pharmaceutical Quality Control

As a certified impurity reference material (≥98% purity) for buflomedil hydrochloride production, ensuring compliance with ICH guidelines.

Scenario 2: Fragrance Development

Integrated into premium perfume formulations at 0.05–0.2% concentration to enhance floral complexity.

4. Client Case Studies

Case Study 1: Nanjing Chemical Reagent Co., Ltd.

Challenge: Required high-purity (>99%) reference standards for GMP-compliant drug manufacturing.
Solution: Supplied batch-certified 1,3,5-Trimethoxybenzene with full traceability documentation.
Outcome: Achieved 99.7% consistency in QC testing across 12-month production cycles.

Case Study 2: Specialty Aroma Solutions

Challenge: Needed thermally stable fragrance components for luxury candle products.
Solution: Customized particle size distribution (20–50 µm) for optimal scent dispersion.
Outcome: Increased product longevity by 40% at 60°C continuous operation.

5. Contact for Technical Support

For bulk pricing, SDS, or custom synthesis requirements:

Email: info@vivalr.com
Tel: (86) 15866781826