Table of Contents
- Product Overview & Specifications
- Key Applications & Industry Uses
- Step-by-Step Usage Guide
- Real-World Case Studies
- Contact for Technical Consultation
3-MERCAPTO-1-PROPANOL CAS 19721-22-3: Technical Specifications
Basic Parameters
| Parameter | Specification |
|---|---|
| Molecular Formula | C3H8OS |
| Molecular Weight | 92.16 g/mol |
| Appearance | Colorless to pale yellow liquid |
| Boiling Point | 195-197°C at 760 mmHg |
| Density | 1.14 g/cm³ at 25°C |
| Flash Point | 73.9°C |
| Purity | ≥98% (GC analysis) |
| Storage | 2-8°C under inert atmosphere |
Comparative Analysis
| Property | 3-Mercapto-1-propanol | 1-Mercapto-2-propanol | 2-Mercaptoethanol |
|---|---|---|---|
| Thiol Content | High reactivity | Moderate | High |
| Thermal Stability | Stable up to 200°C | 160°C | 180°C |
| Solubility in Water | Miscible | Partial | Complete |
Industrial Applications of 3-MERCAPTO-1-PROPANOL
Pharmaceutical Intermediate
Used in synthesis of ACE inhibitors and antiviral drugs through thiol-ene click chemistry. Enables precise control of stereochemistry in chiral molecule production.
Polymer Modification
Functions as chain transfer agent in radical polymerization processes for controlling molecular weight distribution in:
- Acrylic resins
- Polyurethane dispersions
- Epoxy curing systems
Agrochemical Synthesis
Critical component in manufacturing sulfur-containing pesticides and herbicides. Enhances biological activity through thiol-mediated binding.
Electronic Materials
Surface modification agent for semiconductor nanoparticles in QLED displays. Improves quantum yield by 15-20% compared to alternatives.
Operational Guidelines
Pharmaceutical Application Protocol
- Dosage: 1.2-1.5 molar equivalents relative to substrate
- Reaction Temp: 40-60°C under nitrogen atmosphere
- Quenching: Use 5% sodium bicarbonate solution
- Purification: Distillation under reduced pressure (15 mmHg)
Polymerization Process
- Add 0.1-0.5% w/w during initiation phase
- Maintain oxygen-free environment
- Monitor conversion via FTIR at 2550 cm⁻¹ (SH stretch)
Documented Success Cases
Case 1: Pharmaceutical Intermediate Production
| Client | EuroPharma Solutions GmbH |
|---|---|
| Challenge | Low yield (58%) in antiviral drug intermediate synthesis |
| Solution | Implemented 3-Mercapto-1-propanol as nucleophilic catalyst |
| Result | Yield increased to 83% with 99.2% enantiomeric excess |
Case 2: Specialty Polymer Development
| Client | Advanced Polymer Technologies Co., Ltd. |
|---|---|
| Challenge | Uncontrolled branching in acrylic pressure-sensitive adhesives |
| Solution | 0.3% 3-Mercapto-1-propanol as chain transfer agent |
| Result | Achieved narrow PDI of 1.12 and 300% peel strength improvement |
Case 3: Agricultural Formulation Enhancement
| Client | AgroGuard Solutions Inc. |
|---|---|
| Challenge | Rapid degradation of thiol-containing herbicide in storage |
| Solution | Formulated with 2% 3-Mercapto-1-propanol as stabilizer |
| Result | Extended shelf life from 6 months to 18 months at 25°C |
Technical & Commercial Consultation
Contact our chemical engineering team for:
- Custom synthesis protocols
- Bulk pricing (25kg drum to ton quantities)
- Regulatory support (REACH, TSCA compliant)
Email: info@vivalr.com
Tel: (86) 15866781826



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