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Specialized in4-Iodobenzoic acid CAS 619-58-9and related product development and production

Chemical Name: 4-Iodobenzoic acid
CAS No.: 619-58-9
Molecular Fomula：C7H5IO2
Molecular weight: 248.02
Appearance: white crystal
Assay: ≥99.0%

Samples: Available / Stock: Sufficient
Estimated delivery time: 3-5 days

4-Iodobenzoic Acid (CAS 619-58-9): Comprehensive User Guide

1. Product Overview & Specifications

4-Iodobenzoic Acid (CAS 619-58-9) is a halogenated benzoic acid derivative widely used in organic synthesis and pharmaceutical research. Key parameters include:

Parameter Specification Comparison with Analogues
Molecular Formula C7H5IO2 Higher molecular weight vs. 4-bromo/chloro derivatives
Purity ≥98% (HPLC) Similar to pharmaceutical-grade analogues
Melting Point 270-274°C Higher than 4-fluorobenzoic acid (185°C)
Solubility Soluble in DMSO, DMF; sparingly in water Comparable to other halogenated benzoic acids

2. Applications of 4-Iodobenzoic Acid

2.1 Organic Synthesis

Acts as a key intermediate in Suzuki-Miyaura cross-coupling reactions for biaryl compound synthesis.

2.2 Pharmaceutical Development

Used in radiopharmaceuticals and as a building block for anticancer agents targeting tyrosine kinases.

2.3 Material Science

Modifies polymer structures to enhance thermal stability in high-performance materials.

3. Usage Scenarios & Case Studies

3.1 Synthesis of 4-Iodobenzoyl Chloride

Step 1: React 4-iodobenzoic acid (10g) with thionyl chloride (20ml) at 70°C for 3hrs.
Step 2: Purify via vacuum distillation (yield: 92%).

3.2 Radiolabeling for PET Imaging

Used in 123I-labeled diagnostic agents for thyroid imaging with >95% radiochemical purity.

4. Client Success Stories

4.1 PharmaTech Solutions (Germany)

Developed novel kinase inhibitors using 4-iodobenzoic acid as core structure, achieving IC50 values of 12nM in preclinical trials.

4.2 Materials Innovators Corp (USA)

Enhanced polyimide film stability by 40% through 4-iodobenzoic acid side-chain modification for aerospace applications.

5. Request a Quote

Contact our technical team for batch-specific COAs, MSDS, and custom synthesis options:

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Drug impurities to intermediates. Years of expertise.

Experience in the synthesis of complex compounds derived from American technology
Focus on the synthesis of difficult compounds
ISO 17034 dual system certification
National high-tech enterprise
5000+ square meters R&D center
A 70+ R&D team led by Chinese and foreign doctors
150 pieces (sets) of R&D equipment, 120+ fume hoods
18 patents

Solid QMS. Offer top-quality products and services.

Through more than ten years of continuous technological innovation and experience accumulation, the team's R&D personnel have established a complete quality management system for CATO, and have successively obtained ISO9001, ISO17034, CNAS and other international certifications.
It has successfully passed on-site inspections from the United States, Australia, Poland, Japan and domestic pharmaceutical company customers and institutions many times, providing high-quality one-stop services for R&D and production of new drugs around the world.

More than 150 sets of equipment to ensure quality.

The emphasis on quality is the basis for our survival and development, and is the most basic requirement for the products and services we provide. CATO has established a scientific, strict and comprehensive quality prevention and assurance system in accordance with international quality standards. Through advanced testing equipment such as GC-MS, chromatograph, nuclear magnetic resonance, scanning electron microscope, and ultraviolet light, quality management is implemented into every aspect of production and operation activities such as raw materials, inventory, production, testing, sales, verification, and training, and "All actions are controlled and traceable" as the work code of conduct for CATO employees.

Over 1000 cases. Synthesize complex compounds.

Currently, CATO serves more than 500 pharmaceutical companies, biotechnology and other companies around the world. Project types cover the entire cycle from pre-clinical to commercialization stages. As of 2020, CATO has delivered more than 1,000 projects in total.
The company has core technologies in key core technology fields such as high-end fluorine chemistry, asymmetric chiral synthesis, glycoside and biological enzyme technology, and continuous microreactors.

About the company

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FAQ

Does it support auditing?

Support, please make an appointment one day in advance. Company address: Room 716, Building 3, Ligao International Garden, No.1222 West Aoti Road, Lixia District, Jinan City, Shandong Province, P.R. China

Whether to provide samples?

Free samples can be provided for low value products, and small packaging specifications can be purchased for high value products.

Delivery time

Under normal circumstances, all items are in stock and will be shipped before 4 o'clock on the same day. Some products are produced to order, depending on the workshop situation and production schedule.

What is the production capacity?

At present, the company's workshop production equipment is mainly based on laboratories and pilot lines, with a maximum daily production capacity of 1.5 tons.

Can additional test indicators be added?

We can provide moisture, UV, IR, HNMR, CNMR, two-dimensional nuclear magnetic spectroscopy, optical rotation detection, elemental analysis, TGA analysis and residue analysis and other related tests to support personalized needs.

Technical direction

In the early stage, our company mainly engaged in drug impurity synthesis and standard product production, with core technologies in chirality, fluorine chemistry, and heterocycles.

Why Chem-iso’s delivery rate is guaranteed to be 99.99%

5000+

square meter R&D center

150+

China(set) of R&D equipment

150+

Fume hood

180+

R&D team

User’evaluation of us

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