Methyllithium CAS 917-54-4

Chemical Name: Methyllithium
CAS No.: 917-54-4
Molecular Fomula: CH3Li
Molecular weight: 21.98
Appearance: Colorless transparent liquid
Assay: 99%

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Methyllithium (CAS 917-54-4) Comprehensive User Guide

Table of Contents

Product Overview & Specifications

Parameter Methyllithium n-Butyllithium Phenyllithium
CAS Number 917-54-4 109-72-8 591-51-5
Formula CH3Li C4H9Li C6H5Li
Concentration 1.6M in Diethyl Ether 1.6-2.5M in Hexanes 1.8-2.0M in Ether
Pyrophoric Risk High High Moderate

Key Applications & Industrial Uses

Core Function: Powerful methylating agent and strong base for organometallic reactions

  • Pharmaceutical intermediates synthesis
  • Polymer initiator in advanced material production
  • Catalyst in asymmetric synthesis
  • Reagent for ketone/enolate chemistry

Operational Best Practices

Critical Handling Requirements:

  • Maintain inert atmosphere (Ar/N2)
  • Storage at -20°C in amber bottles
  • Use flame-resistant equipment

Industry Application Cases

Case 1: Vitamin B1 synthesis via nucleophilic addition

Reaction Scheme: RCHO + CH3Li → RCH(OH)CH3

Client Success Stories

Client Industry Application Outcome
PharmaCore Ltd. Pharmaceuticals Antipsychotic API synthesis Yield increased 22%
PolyNovo Materials Advanced Materials Conductive polymer initiator 15% cost reduction

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Contact our technical team:

Email: info@vivalr.com
Tel: (86) 15866781826

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