Benzimidazole CAS 51-17-2

Chemical Name: Benzimidazole
CAS No.: 51-17-2
Molecular Fomula: C7H6N2
Molecular weight: 118.14
Appearance: white powder
Assay: 99%

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Benzimidazole CAS 51-17-2: Comprehensive User Guide

1. Product Overview & Specifications

Benzimidazole (CAS 51-17-2) is a heterocyclic aromatic compound with the molecular formula C7H6N2 and a molecular weight of 118.14 g/mol. It appears as white crystalline flakes with a melting point of 170–172°C and a boiling point exceeding 360°C.

Parameter Benzimidazole Benzotriazole Imidazole
CAS Number 51-17-2 95-14-7 288-32-4
Solubility Soluble in hot water, ethanol; insoluble in benzene Soluble in alkaline solutions Highly water-soluble
Primary Use Pharmaceutical intermediates Corrosion inhibition Organic synthesis

Key Specifications:
– Purity: 98–99% (industrial/pharmaceutical grade)
– Storage: 2–8°C in airtight containers
– Safety: Non-flammable but may cause eye/skin irritation

2. Key Applications

Pharmaceutical Industry

Core building block for:
– Anthelmintic drugs: Albendazole, Mebendazole
– Proton pump inhibitors: Omeprazole, Pantoprazole
– Antiviral/anticancer drug development

Agricultural Chemistry

– Intermediate for fungicides and pesticides
– Component in plant growth regulators

Material Science

– Precursor for porous polymers (CO2 separation materials)
– Coordination complexes in catalysis

3. Usage Scenarios

Pharmaceutical Synthesis

Example: In omeprazole production:
1. Benzimidazole → Sulfonation → Coupling with pyridine derivative
2. Final purification for acid-resistant enteric coating

Analytical Chemistry

– Colorimetric determination of cobalt ions
– Chelating agent in metal ion chromatography

4. Industry Case Studies

Case 1: Pharmaceutical Manufacturer (Hubei, China)

Challenge: Scale-up of Albendazole production
Solution: Optimized benzimidazole purification (99.5% purity)
Result: 22% yield improvement, meeting WHO GMP standards

Case 2: Polymer Research Lab (Germany)

Application: CO2-selective adsorption membranes
Process: Synthesized benzimidazole-linked polymers (BILPs)
Performance: 93% CO2/N2 selectivity at 25°C

5. Contact Information

For technical specifications, bulk orders, or custom synthesis requirements:
Email: info@vivalr.com
Phone: (86) 15866781826
Availability: 25kg drums; custom packaging available

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