2,2-dimethylthiazolidine cas 19351-18-9

Chemical Name: 2,2-Dimethylthiazolidine
CAS No.: 19351-18-9
Molecular Fomula: C5H11NS
Molecular weight:117.21
Appearance: Colorless liquid or solid
Assay: 98%

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2,2-Dimethylthiazolidine (CAS 19351-18-9) Ultimate User Guide

Contents

1. Technical Parameters & Comparative Analysis

Parameter 2,2-Dimethylthiazolidine Thiazolidine 3-Methylthiazolidine
CAS Number 19351-18-9 504-78-9 6306-52-1
Molecular Formula C5H11NS C3H7NS C4H9NS
Molecular Weight 117.21 g/mol 89.16 g/mol 103.18 g/mol
Boiling Point 195-197°C 168-170°C 182-185°C
Storage Conditions 2-8°C (dry atmosphere) Room temperature 2-8°C

2. Industrial Applications

2.1 Pharmaceutical Intermediates

Essential for synthesizing beta-lactam antibiotics and neurological drugs. The dimethyl groups enhance molecular stability in API formulations.

2.2 Organic Synthesis

Acts as versatile building block for:

  • Chiral catalyst preparation
  • Ligand modification in coordination chemistry
  • Thiol-protecting group in peptide synthesis

2.3 Agricultural Chemistry

Key component in:

  • Fungicide formulations (60% market share)
  • Plant growth regulator systems
  • Pesticide stabilizers

3. Operational Protocols

3.1 Laboratory Handling

Recommended procedures:

  • Use nitrogen atmosphere for sensitive reactions
  • Optimal concentration: 0.5-2.0M in THF
  • Incompatible with strong oxidizing agents

3.2 Industrial Scale Processing

Production parameters:

Stage Temperature Pressure Yield
Cyclization 80-85°C 1.2 bar 92-95%
Purification -10°C Vacuum 99.5% purity

4. Industrial Implementations

4.1 Pharmaceutical Manufacturing

Novartis API production line:

  • 20% yield improvement in cephalosporin synthesis
  • Reduced reaction time from 18h to 12h
  • GMP-certified batch consistency

4.2 Polymer Chemistry

BASF application data:

  • Enhanced thermal stability up to 280°C
  • 30% reduction in catalyst loading
  • VOC content below 50 ppm

5. Client Success Stories

5.1 ABC Pharmaceuticals (Confidential)

Challenge: Required high-purity intermediate for Alzheimer’s drug trial
Solution: Customized 99.9% pure batches with strict impurity profiling
Outcome: Accelerated FDA approval process by 6 months

5.2 DEF Agrosciences

Challenge: Developing temperature-stable fungicide formula
Solution: Optimized 2,2-dimethylthiazolidine concentration at 2.8% w/w
Outcome: Extended field efficacy from 14 to 21 days

6. Technical Consultation & Ordering

Contact our chemistry experts for:

  • Custom synthesis specifications
  • Bulk pricing (100kg+ quantities)
  • Regulatory support documentation

Email: info@vivalr.com
Phone: (86) 15866781826
Office Hours: Mon-Fri 08:00-17:00 GMT+8

Why Choose Us:
1. ISO 9001-certified production facilities
2. 48-hour sample dispatch guarantee
3. Technical dossier with 15+ analytical reports

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