Polyvinylpolypyrrolidone Crospovidone cross-linked PVPP CAS 25249-54-1

Appearance: white powder
Standard: CP; USP; EP
Packaging: 1kg, 5kg, 20kg/bag
Sample: Available
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COA of Polyvinylpyrrolidone cross-linked

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Product Overview

Polyvinylpolypyrrolidone (Crospovidone, PVPP) CAS 25249-54-1

Cross-linked polyvinylpyrrolidone (PVPP) is a water-insoluble polymer with exceptional adsorption capabilities and swelling properties. This white hygroscopic powder exhibits:

  • Molecular Formula: (C6H9NO)n
  • CAS Registry: 25249-54-1
  • USP/EP Compliance: Meets USP 43 and EP 10.0 standards
  • Thermal Stability: Decomposes at 300°C+

Technical Specifications Comparison

Parameter Pharma Grade Food Grade Industrial Grade
Purity ≥99.5% ≥99% ≥97%
Particle Size 50-150μm 100-300μm 200-500μm
Swelling Capacity 5.0-7.0 ml/g 4.5-6.5 ml/g 3.5-5.5 ml/g

Industrial Applications

Pharmaceutical Sector

  • Superdisintegrant in oral solid dosages (tablets/capsules)
  • Dissolution rate enhancer for poorly soluble APIs

Beverage Industry

  • Polyphenol removal in beer stabilization (0.5-2.0g/hL)
  • Clarification agent in fruit juices and wines

Operational Guidelines

Tablet Formulation Protocol

  1. Blend with API and excipients (2-5% w/w)
  2. Compress at 10-20 kN force
  3. Disintegration time: <3 minutes (USP)

Client Implementation Cases

Case 1: Shaanxi Shengkang Biotechnology

  • Application: High-speed tablet production line
  • Result: 40% reduction in disintegration time

Case 2: Ronghe New Materials

  • Application: Craft beer stabilization
  • Result: Extended shelf life by 60%

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