1-Bromo-4-Chlorobutane CAS 6940-78-9

1-Bromo-4-Chlorobutane (CAS 6940-78-9): Technical Guide & Applications

Table of Contents

• 1. Product Specifications & Comparative Analysis
• 2. Industrial Applications & Functional Mechanisms
• 3. Operational Guidelines & Safety Protocols
• 4. Case Studies in Pharmaceutical Synthesis
• 5. Client Success Stories
• 6. Request Customized Solutions

1. Product Specifications & Comparative Analysis

2. Industrial Applications & Functional Mechanisms

2.1 Pharmaceutical Intermediate

Critical precursor in synthesis of:

• Atypical antipsychotics: Brexpiprazole, Aripiprazole API production
• Neuroleptic agents: Facilitates alkylation in dopamine D2 receptor modulators

2.2 Specialty Chemistry

• Cross-coupling reactions: Buchwald-Hartwig aminations
• Phase-transfer catalysis: Quaternary ammonium compound synthesis

2.3 Fragrance Engineering

• Macrocyclic musk derivatives: Alkyl chain elongation agent
• Terpene modifications: Halogenation control point

3. Operational Guidelines & Safety Protocols

4. Case Studies in Pharmaceutical Synthesis

4.1 Brexpiprazole Manufacturing

Process optimization achieving 92% yield:

• Step 1: Nucleophilic substitution with piperazine derivative
• Step 2: Purification via fractional distillation (purity >99.5%)

4.2 Continuous Flow Chemistry

Microreactor system implementation:

• 30% reduction in reaction time
• Waste generation lowered by 45%

5. Client Success Stories

5.1 Top 10 Pharma Company (EU)

• Application: Aripiprazole scale-up
• Results: 15% batch consistency improvement
• Annual consumption: 8 MT

5.2 Fragrance Leader (USA)

• Application: Musk intermediate synthesis
• Outcome: 99.8% halogenation selectivity
• Ongoing partnership since 2022

6. Request Customized Solutions

Optimize your synthesis with our technical expertise:

• Email: info@vivalr.com
• Tel: (86) 15866781826
• Services: Custom purification, stable isotope labeling