3-nitroacetophenone cas 121-89-1
Chemical Name: 3-Nitroacetophenone
CAS No.: 121-89-1
Molecular Fomula: C8H7NO3
Molecular weight: 165.15
Appearance: Slightly yellow to off-white crystalline
Assay: 99%
related documents:
COA of 3-nitroacetophenone
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3-Nitroacetophenone (CAS 121-89-1) Ultimate Buyer’s Guide
Table of Contents
1. Technical Specifications & Comparative Analysis
| Parameter | 3-Nitroacetophenone | 2-Nitroacetophenone | 4-Nitroacetophenone |
|---|---|---|---|
| CAS Number | 121-89-1 | 577-59-3 | 100-19-6 |
| Molecular Formula | C8H7NO3 | C8H7NO3 | C8H7NO3 |
| Appearance | Yellow crystalline powder | Pale yellow solid | White to off-white crystals |
| Melting Point | 72-75°C | 63-65°C | 80-82°C |
| Key Applications | Pharma intermediates, Agrochemicals | Dye manufacturing | Polymer modifiers |
2. Industrial Applications & Functional Uses
Pharmaceutical Manufacturing
Primary intermediate in synthesis of:
- Antidepressant APIs: Venlafaxine precursors
- Antibacterial agents: Cephalosporin derivatives
- Anticancer compounds: Kinase inhibitor scaffolds
Agrochemical Production
Critical component for:
- Herbicide formulations: Nitroaromatic synthesis
- Insect growth regulators: Chitin synthesis inhibitors
- Fungicide intermediates: Systemic crop protection agents
3. Implementation Case Studies
Case Study 1: Pharmaceutical Intermediate Synthesis
Challenge: A European API manufacturer required high-purity nitroacetophenone derivatives for GMP-compliant production.
Solution: Customized synthesis with ≥99.5% purity and residual solvent control <50ppm.
Outcome: 22% yield improvement in final API crystallization process.
Case Study 2: Agrochemical Formulation
Challenge: Asian agrochemical producer needed thermally stable nitro intermediates for slow-release herbicides.
Solution: Modified crystallization process achieving decomposition temperature >200°C.
Result: 18-month shelf life extension in tropical climates.
4. Verified Client Success Stories
Client 1: Top-tier Pharmaceutical Company (Germany)
- Application: Antiviral drug intermediate synthesis
- Volume: 8 MT/year continuous supply
- Key Benefit: Reduced catalyst loading by 40% through optimized particle size distribution
Client 2: Specialty Chemicals Manufacturer (USA)
- Application: Electronic chemicals production
- Technical Achievement: Achieved Class 100 cleanroom compatibility
- Quality Parameters: Heavy metal content <1ppm, particle size D90 <50μm
5. Expert Consultation & Quotation
For technical specifications sheets, regulatory documentation, or bulk pricing:
Contact our chemical engineering team:
- Email: info@vivalr.com
- Tel: (86) 15866781826
Request customized solutions for:
- GMP-grade pharmaceutical intermediates
- Custom particle engineering services
- Regulatory support (REACH, TSCA compliance)



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