4-Cyanobenzoic Acid (CAS 619-65-8) Comprehensive Guide
Contents
- 1. Product Specifications & Comparative Analysis
- 2. Industrial Applications
- 3. Operational Guidelines
- 4. Application Case Studies
- 5. Client Success Stories
- 6. Commercial Inquiry Process
1. Product Specifications & Comparative Analysis
| Parameter | 4-Cyanobenzoic Acid | Similar Derivatives |
|---|---|---|
| CAS Number | 619-65-8 | N/A |
| Molecular Formula | C8H5NO2 | Varies |
| Purity Grade | ≥98% (HPLC) | 90-97% |
| Thermal Stability | Up to 250°C | 200-220°C |
2. Industrial Applications
Pharmaceutical Intermediates
Critical precursor for angiotensin-converting enzyme (ACE) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs).
Advanced Polymer Synthesis
Essential monomer for high-performance polyamides and liquid crystal polymers (LCPs) with enhanced thermal resistance.
3. Operational Guidelines
Storage Protocols
– Maintain in sealed containers under inert gas atmosphere
– Optimal storage temperature: 2-8°C
Reaction Handling
Recommended solvent systems:
1. DMF/H2O (3:1 v/v) for nucleophilic substitutions
2. THF/DCM mixtures for coupling reactions
4. Application Case Studies
Case 1: Antihypertensive Drug Synthesis
Used as key intermediate in 8-step synthesis of Lisinopril analogues, achieving 92% overall yield.
Case 2: Specialty Polymer Production
Enabled creation of heat-resistant polyamide fibers (Tm 315°C) for automotive components.
5. Client Success Stories
PharmaCorp Solutions
“Implemented 4-Cyanobenzoic Acid in our ACE inhibitor production line, reducing synthesis steps from 12 to 9 while maintaining 99.5% API purity.”
PolyTech Industries
“Achieved 23% improvement in polymer tensile strength using this compound as a chain extender in our LCP formulations.”
6. Commercial Inquiry Process
Procurement Options
| Package Size | Purity | Lead Time |
|---|---|---|
| 100g | 98% | 3-5 days |
| 1kg | 99% | 7-10 days |
Contact Information
Email: info@vivalr.com
Tel: (86) 15866781826
Request custom synthesis options or bulk pricing quotes through our 24/7 response team.



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