4-Cyanobenzoic Acid Cas 619-65-8

Chemical Name: 4-Cyanobenzoic acid
CAS No.: 619-65-8
Molecular Fomula: C8H5NO2
Molecular weight: 147.13
Appearance: Off white powder
Assay: 98%

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4-Cyanobenzoic Acid (CAS 619-65-8) Comprehensive Guide

Contents

1. Product Specifications & Comparative Analysis

Parameter 4-Cyanobenzoic Acid Similar Derivatives
CAS Number 619-65-8 N/A
Molecular Formula C8H5NO2 Varies
Purity Grade ≥98% (HPLC) 90-97%
Thermal Stability Up to 250°C 200-220°C

2. Industrial Applications

Pharmaceutical Intermediates

Critical precursor for angiotensin-converting enzyme (ACE) inhibitors and non-steroidal anti-inflammatory drugs (NSAIDs).

Advanced Polymer Synthesis

Essential monomer for high-performance polyamides and liquid crystal polymers (LCPs) with enhanced thermal resistance.

3. Operational Guidelines

Storage Protocols

– Maintain in sealed containers under inert gas atmosphere
– Optimal storage temperature: 2-8°C

Reaction Handling

Recommended solvent systems:
1. DMF/H2O (3:1 v/v) for nucleophilic substitutions
2. THF/DCM mixtures for coupling reactions

4. Application Case Studies

Case 1: Antihypertensive Drug Synthesis

Used as key intermediate in 8-step synthesis of Lisinopril analogues, achieving 92% overall yield.

Case 2: Specialty Polymer Production

Enabled creation of heat-resistant polyamide fibers (Tm 315°C) for automotive components.

5. Client Success Stories

PharmaCorp Solutions

“Implemented 4-Cyanobenzoic Acid in our ACE inhibitor production line, reducing synthesis steps from 12 to 9 while maintaining 99.5% API purity.”

PolyTech Industries

“Achieved 23% improvement in polymer tensile strength using this compound as a chain extender in our LCP formulations.”

6. Commercial Inquiry Process

Procurement Options

Package Size Purity Lead Time
100g 98% 3-5 days
1kg 99% 7-10 days

Contact Information

Email: info@vivalr.com
Tel: (86) 15866781826
Request custom synthesis options or bulk pricing quotes through our 24/7 response team.

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