1,8-Diazabicyclo[5,4,0] undec-7-ene / DBU Cas 6674-22-2

Chemical Name: 1,8-Diazabicyclo[5,4,0] undec-7-ene; DBU
CAS No:6674-22-2
Molecular Formula: C9H16N2
Molecular Weight: 152.24
Appearance: Yellowish liquid
Assay: 99%

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1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU) Cas 6674-22-2: Comprehensive User Guide

1. Product Overview & Specifications

1,8-Diazabicyclo[5.4.0]undec-7-ene (DBU), CAS 6674-22-2, is a highly versatile bicyclic amidine catalyst widely used in organic synthesis, polymer production, and pharmaceutical manufacturing. Below are its key specifications:

Parameter DBU (Cas 6674-22-2) Common Alternatives
Molecular Formula C₉H₁₆N₂ Varies by compound
Molecular Weight 152.24 g/mol ~120-180 g/mol
Appearance Colorless to pale yellow liquid Depends on base type
Purity ≥98% (GC) Typically 95-99%
Boiling Point 80-82°C (0.5 mmHg) Lower thermal stability

2. Key Applications & Use Cases

2.1 Organic Synthesis

DBU excels as a non-nucleophilic base for:

  • Catalyzing esterification and transesterification
  • Facilitating Heck and Suzuki couplings
  • Removing acid-labile protecting groups

2.2 Polymer Chemistry

Critical in polyurethane/polyurea production for:

  • Controlling reaction kinetics
  • Reducing gelation time
  • Improving thermal stability

3. Industry Case Studies

Case 1: Pharmaceutical Intermediate Synthesis

Client: EuroPharma Solutions GmbH

Challenge: Low yield (42%) in API step using DIPEA

Solution: Switched to DBU at 1.2 eq

Result: 89% yield, 99.2% purity

Case 2: Specialty Polymer Production

Client: Advanced Materials Co., Ltd.

Challenge: Premature curing in polyurethane formulation

Solution: 0.8% DBU as latency controller

Result: 35% longer pot life, VOC reduction

4. Request a Quote

VIVALR Chemical supplies high-purity DBU (Cas 6674-22-2) with:

  • Batch-specific COA
  • Technical consultation
  • Global logistics support

Contact our experts:

Email: info@vivalr.com
Tel: (86) 15866781826

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