1-Phenyl-2-pyrrolidinone (CAS 4641-57-0): Comprehensive Product Guide
Table of Contents
1. Product Overview & Specifications
| Parameter | Details |
|---|---|
| CAS Number | 4641-57-0 |
| Molecular Formula | C10H11NO |
| Molecular Weight | 161.20 g/mol |
| Synonyms | N-Phenylpyrrolidone, 1-Phenylpyrrolidin-2-one, N-Phenylbutyrolactam |
| Purity | ≥99% (HPLC) |
| Appearance | White to off-white crystalline powder |
2. Applications & Industrial Uses
Key Applications:
- Pharmaceutical Intermediate: Used in synthesizing GABA analogs and neuroactive compounds.
- Research Chemical: Studied for its sedative properties in preclinical models (50-100 mg/kg IV in rodents).
- Behavioral Studies: Reduces exploratory behavior in rats and inhibits emotional responses in cats/dogs.
- Industrial Solvent: Acts as a high-polarity aprotic solvent in specialty chemical synthesis.
3. Biological Activity & Mechanism
Pharmacological Profile:
- Target: Modulates GABAergic pathways without affecting baroreceptor reflexes.
- Dosage: Effective at 50-100 mg/kg (intravenous) in rodent models.
- Safety: Reduces pressor responses to emotional stress while maintaining normal reflex functions.
4. Supplier Information
| Supplier | Specifications | Packaging |
|---|---|---|
| Meryer (China) | Catalog No. M40520, 99% purity | 1g, 5g, 25g bottles |
| Shanghai Jinlin Biotech | GR-grade, HPLC-verified | Custom quantities (mg to kg scale) |
5. Inquiry & Contact
For technical specifications, bulk pricing, or COA requests:
- Email: info@vivalr.com
- Tel: (86) 15866781826 (Mon-Fri, 9 AM – 5 PM CST)



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