5-Amino-2-Fluorobenzonitrile (CAS 53312-81-5) Comprehensive Guide
Table of Contents
- 1. Product Overview & Specifications
- 2. Key Applications & Industrial Uses
- 3. Technical Parameter Comparison
- 4. Synthesis & Manufacturing Process
- 5. Application Case Studies
- 6. Verified Customer Implementations
- 7. Procurement Guidance
1. Product Overview & Specifications
| Parameter | Specification |
|---|---|
| CAS Number | 53312-81-5 |
| Molecular Formula | C7H5FN2 |
| Molecular Weight | 136.13 g/mol |
| Appearance | White to off-white crystalline powder |
| Purity | ≥98.5% (HPLC) |
| Melting Point | 89-92°C |
| Storage Conditions | 2-8°C in airtight container |
2. Key Applications & Industrial Uses
5-Amino-2-fluorobenzonitrile serves as critical intermediate in:
- Pharmaceutical synthesis (kinase inhibitors, anticancer agents)
- Agrochemical production (herbicide intermediates)
- Advanced material development (liquid crystal polymers)
- Organic electronics (semiconductor precursors)
3. Technical Parameter Comparison
| Vendor | Purity | Price/kg | Lead Time |
|---|---|---|---|
| Vivalr Chemicals | 99.2% | $1,850 | 2 weeks |
| Supplier B | 98.5% | $2,100 | 4 weeks |
| Supplier C | 97.0% | $1,950 | 3 weeks |
4. Synthesis & Manufacturing Process
Industrial production follows this optimized pathway:
- Fluorination of 2-chlorobenzonitrile
- Catalytic amination reaction
- Crystallization purification
- Quality control testing
5. Application Case Studies
Case 1: Anticancer Drug Development
Used in synthesis of third-generation EGFR inhibitors showing 78% improved bioavailability…
Case 2: High-Performance Polymer Production
Key monomer in heat-resistant polyamides for aerospace applications…
6. Verified Customer Implementations
PharmaTech Solutions
“Vivalr’s 5-amino-2-fluorobenzonitrile reduced our API production costs by 22%…”
Materials Innovators Corp
“Consistent purity enabled breakthrough in flexible display technologies…”
7. Procurement Guidance
For technical specifications or bulk pricing:
Email: info@vivalr.com
Phone: (86) 15866781826
Request quote with:
- Required quantity
- Packaging specifications
- Delivery timeline
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