Butyl 4-Aminobenzoate (CAS 94-25-7) Comprehensive Guide
Table of Contents
- Product Specifications & Comparative Analysis
- Industrial Applications & Functional Mechanisms
- Operational Protocols & Formulation Guidelines
- Application Case Studies
- Enterprise Implementation Examples
- Technical Consultation & Procurement Guidance
Product Specifications & Comparative Analysis
| Parameter | Butyl 4-Aminobenzoate | Benzocaine (Comparative) |
|---|---|---|
| CAS Number | 94-25-7 | 94-09-7 |
| Molecular Formula | C11H15NO2 | C9H11NO2 |
| Molecular Weight | 193.24 g/mol | 165.19 g/mol |
| Appearance | White crystalline powder | White crystalline powder |
| Lipid Solubility | High (LogP 2.87) | Moderate (LogP 2.41) |
| Melting Point | 57-60°C | 88-90°C |
Industrial Applications & Functional Mechanisms
Pharmaceutical Applications
As topical anesthetic in:
- Dermatological preparations (5-20% concentration)
- Otic formulations for ear pain management
- Proctological ointments
Cosmetic Formulations
- UV-filter in SPF products (maximum 5% under EU regulation)
- Stabilizer in liposomal delivery systems
Industrial Uses
- Plasticizer in polymer coatings
- Intermediate for specialty chemicals
Operational Protocols
Pharmaceutical Preparation
- Base preparation: Mix 70% petroleum jelly with 15% mineral oil
- Incorporate 10% Butyl 4-Aminobenzoate at 40°C
- Homogenize for 30 minutes at 2,500 rpm
Application Case Studies
Case 1: Dermatological Cream
Challenge: Required sustained anesthetic effect (>6 hours) for laser therapy aftercare
Solution: 15% Butyl 4-Aminobenzoate in emulsion base
Result: 68% pain reduction (VAS scale) sustained for 7.2 hours
Case 2: Industrial Coating
Challenge: Prevent plasticizer migration in PVC medical tubing
Solution: 2.5% additive in polymer matrix
Result: 40% reduction in plasticizer loss after 30-day immersion
Enterprise Implementations
PharmaCorp Solutions
Application: Topical analgesic for veterinary use
Implementation: 8% concentration in roll-on formulation
Outcome: 35% faster application time with 22% cost reduction
CosmeTech International
Application: SPF booster in anti-aging serum
Implementation: 3% microencapsulated form
Outcome: 50% UVB protection enhancement without whitening effect
Technical Consultation
Contact our formulation specialists for application-specific guidance:
Email: info@vivalr.com
Phone: (86) 15866781826
Request customized technical dossier including:
– Regulatory compliance documentation
– Stability test reports (ICH guidelines)
– Compatibility matrices



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