eprosartan mesylate cas 144143-96-4

Chemical Name: Eprosartan mesylate
CAS No.: 144143-96-4
Molecular Formula: C24H28N2O7S2
Molecular weight:520.61832
Appearance:A white to off-white colour powder
Assay: 98%

  ... 正在查看此商品

  分享
Guaranteed Safe Checkout

Table of Contents

1. Eprosartan Mesylate: Key Specifications & Comparative Analysis

Parameter Eprosartan Mesylate Losartan Potassium Valsartan
CAS Number 144143-96-4 124750-99-8 137862-53-4
Molecular Formula C23H24N2O4S·CH4O3S C22H22ClKN6O C24H29N5O3
Bioavailability 13% (Oral) 25-35% 10-35%
Half-Life 5-9 hours 6-9 hours 6-7 hours
Protein Binding 98% 99.7% 95%

2. Therapeutic Applications & Mechanism of Action

Primary Indications:

  • Essential hypertension management
  • Diabetic nephropathy adjuvant therapy
  • Cardiovascular risk reduction in high-risk patients

Pharmacodynamics:
Selective AT1 receptor antagonist inhibiting angiotensin II vasoconstriction. Unique sulfonyl carbamate structure enables prolonged receptor occupancy compared to tetrazole-containing ARBs.

3. Clinical Implementation Case Studies

Case 1: Hypertension Management
A 2023 multicenter trial (n=1,240) demonstrated 24-hour BP control in 68% of patients receiving 600mg BID dosage, with 39% reduction in nocturnal hypertension episodes.

Case 2: Renal Protection
University Hospital Basel (2024) reported 27% decrease in albuminuria levels among diabetic patients after 36-week eprosartan regimen (400mg QD).

4. Enterprise Utilization Examples

PharmaCorp Solutions
– Application: Bulk API manufacturing for antihypertensive combos
– Annual Consumption: 850kg
– Outcome: Achieved 99.7% purity in final formulation batches

HealthSolutions Inc.
– Application: Clinical trial material for pediatric hypertension study
– Scale: 120kg for Phase III trials
– Regulatory Status: Successfully passed FDA pre-approval inspection

5. Procurement Consultation

For technical specifications sheets, COA documentation, or bulk pricing:
Email: info@vivalr.com
Tel: (86) 15866781826

Request current lead times, regulatory support options, and stability data packages.

0.00
0 条评论
5
0
4
0
3
0
2
0
1
0
成为第一个评论 “eprosartan mesylate cas 144143-96-4”

您的邮箱地址不会被公开。 必填项已用 * 标注

这是必填栏。

这是必填栏。

这是必填栏。

评论

目前还没有评论。

类别 
我的购物车
愿望清单
最近浏览
类别
Wait! before you leave…
Get 30% off for your first order
CODE30OFFCopy to clipboard
Use above code to get 30% off for your first order when checkout
比较产品 (0 产品)