Tetrabutylammonium Fluoride Cas 429-41-4

Chemical Name: Tetrabutylammonium fluoride
CAS No.: 429-41-4 / 87749-50-6
Molecular Formula: C16H36FN
Molecular weight:261.46
Appearance: White or yellow ceraceous
Assay: ≥98%
related documents:

COA of Tetrabutyl ammonium fluoride
TDS of Tetrabutyl ammonium fluoride

Request for product documents

  ... 正在查看此商品

  分享
Guaranteed Safe Checkout

Tetrabutylammonium Fluoride (CAS 429-41-4): Technical Guide & Application Insights

1. Product Specifications & Comparative Analysis

Parameter Tetrabutylammonium Fluoride Alternative Fluorination Agents
CAS Number 429-41-4 Varies by compound
Molecular Formula C16H36FN Typically simpler structures
Molecular Weight 261.462 g/mol Generally lower MW
Appearance White to yellow hygroscopic wax Powders/liquids common
Melting Point 62-63°C Wider range (50-300°C)
Solubility THF, water, acetonitrile Limited solvent compatibility

2. Key Applications & Functional Properties

Core Functions:

  • Silicon Deprotection: Efficient cleavage of silyl ether protecting groups under mild conditions
  • Fluorination Catalyst: Enables nucleophilic fluorination in SN2 reactions
  • Phase Transfer Agent: Facilitates reactions between immiscible phases in alkylation/elimination processes

Industry-Specific Uses:

  • Pharmaceutical intermediates synthesis
  • Liquid crystal material production
  • Specialty polymer modification

3. Practical Use Cases in Organic Synthesis

Case 1: Deprotection in Antiviral Drug Synthesis

Used at 0.1M concentration in THF to remove tert-butyldimethylsilyl (TBDMS) groups from nucleoside intermediates, achieving >95% yield under nitrogen atmosphere.

Case 2: Fluorinated Polymer Production

Employed as phase transfer catalyst (0.5 mol%) in interfacial polymerization of fluorinated diamines, reducing reaction time from 48h to 12h.

4. Industry Client Success Stories

Wuhan Jiye Sheng Chemical Co., Ltd.

  • Application: Manufacturing of liquid crystal intermediates
  • Result: 30% reduction in side products through optimized TBAF-mediated fluorination
  • Scale: 500kg/month production

Hubei Yaoshuoquan Chemical

  • Application: Synthesis of antitumor drug candidates
  • Challenge: Selective deprotection of sensitive substrates
  • Solution: Custom 1M THF solution with stabilized moisture content <50ppm

5. Contact for Customized Solutions

Request technical specifications sheets or discuss bulk pricing:

Email: info@vivalr.com
Tel: (86) 15866781826

0.00
0 条评论
5
0
4
0
3
0
2
0
1
0
成为第一个评论 “Tetrabutylammonium Fluoride Cas 429-41-4”

您的邮箱地址不会被公开。 必填项已用 * 标注

这是必填栏。

这是必填栏。

这是必填栏。

评论

目前还没有评论。

类别 
我的购物车
愿望清单
最近浏览
类别
Wait! before you leave…
Get 30% off for your first order
CODE30OFFCopy to clipboard
Use above code to get 30% off for your first order when checkout
比较产品 (0 产品)