brefeldin a cas 20350-15-6

Brefeldin A (CAS 20350-15-6): Comprehensive Product Guide

Table of Contents

• 1. Product Overview & Specifications
• 2. Applications & Industrial Uses
• 3. Operational Guidelines
• 4. Case Studies
• 5. Client Success Stories
• 6. Contact for Quotation

1. Product Overview & Specifications

Brefeldin A (CAS 20350-15-6) is a lactone antibiotic produced by fungal species, widely used in biomedical research for its ability to inhibit protein transport and induce Golgi apparatus disruption.

2. Applications & Industrial Uses

Brefeldin A is critical in:

• Cancer Research: Induces apoptosis in tumor cells.
• Virology Studies: Inhibits viral replication mechanisms.
• Drug Discovery: Used in high-throughput screening assays.

3. Operational Guidelines

Recommended Protocols:

• Dissolve in DMSO at 10 mg/mL stock concentration.
• Working concentration range: 1-10 μM depending on cell type.
• Store aliquots at -20°C; avoid freeze-thaw cycles.

4. Case Studies

Case Study 1: University of Cambridge (2023) used Brefeldin A to enhance cisplatin efficacy in ovarian cancer cells, achieving 40% higher apoptosis rates.

Case Study 2: NIH-funded project demonstrated Brefeldin A’s role in blocking SARS-CoV-2 spike protein maturation in vitro.

5. Client Success Stories

Client A: Leading German biotech company reduced viral titer by 99% in antiviral assays using our GMP-grade Brefeldin A.

Client B: Japanese research institute successfully mapped ER-Golgi trafficking pathways with batch-specific analytical data provided.

6. Contact for Quotation

Request bulk pricing or custom synthesis options:

• Email: info@vivalr.com
• Phone: (86) 15866781826