Congo Red (CAS 573-58-0): Comprehensive Technical Guide
Table of Contents
1. Product Specifications & Comparative Analysis
| Parameter | Congo Red | Alternative Dyes |
|---|---|---|
| CAS Number | 573-58-0 | Varies by compound |
| Molecular Formula | C32H22N6Na2O6S2 | Dye-specific |
| Molecular Weight | 696.66 g/mol | 300-800 g/mol (typical) |
| Appearance | Red crystalline powder | Varies (liquid/powder) |
| Solubility |
|
Dependent on polarity |
| pH Sensitivity | 3.0-5.2 (Color transition) | Varies with indicator |
2. Functional Applications
Biomedical Research
- Amyloid Detection: Gold standard for identifying β-pleated sheet structures in tissue samples
- Protein Aggregation Studies: Monitors misfolded protein accumulation in mutant cell lines
- Histochemical Staining: Validated for HSPB1 mutant analysis in neurodegenerative research
Industrial Applications
- Textile Dyeing: Superior affinity for cellulose fibers (cotton, rayon)
- Paper Manufacturing: Preferred for specialty paper products and security printing
- Leather Treatment: Provides colorfastness in pH 3.0-5.0 environments
3. Implementation Scenarios
Laboratory Protocols
- Amyloid Identification: 0.2% aqueous solution in PBS buffer (pH 7.4)
- Microscopy Preparation: 5-minute staining at 25°C with ethanol dehydration
Industrial Processes
- Textile Dye Bath: 1-3% w/w concentration at 80-90°C
- Paper Coating: 0.5-1.5% solution with starch binder
4. Client Case Studies
Case 1: Biomedical Research Institute
- Application: Neurodegenerative disease model development
- Implementation: Identified β-amyloid plaques in transgenic mouse brain sections
- Outcome: 92% correlation with immunohistochemistry results
Case 2: Specialty Paper Manufacturer
- Application: Security document production
- Implementation: Achieved ISO 17025-compliant color consistency
- Outcome: Reduced dye consumption by 18% through optimized pH control
5. Contact for Technical Consultation
For formulation optimization or bulk procurement specifications:
| Contact Method | Details |
|---|---|
| Technical Support | Email: info@vivalr.com |
| Procurement Inquiry | Phone: (86) 15866781826 |
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