Folinic acid CAS 58-05-9
Assay: ≥97.5%
Synonyms: 5-Formyltetrahydrofolic acid
Appearance: Off-white to greenish yellow powder
Capacity: 5kg per month
Packaging: 1 kg/bag
Sample: available
related documents:
COA of Folinic Acid CAS 58-05-9
TDS of Folinic Acid CAS 58-05-9
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Folinic Acid (CAS 58-05-9) Comprehensive User Guide: Applications, Case Studies, and Technical Insights
Table of Contents
1. Product Overview & Specifications
| Parameter | Folinic Acid (CAS 58-05-9) | Folic Acid | Calcium Folinate |
|---|---|---|---|
| Chemical Name | Leucovorin | Pteroylglutamic acid | Calcium leucovorin |
| Bioavailability | Directly active form | Requires enzymatic conversion | Pre-activated formulation |
| pH Stability | 6.0-8.0 | 4.0-7.0 | 7.0-9.0 |
| Storage Temp | 2-8°C | Room temperature | 2-8°C |
2. Key Applications of Folinic Acid
2.1 Pharmaceutical Applications
As a reduced folate formulation, Folinic Acid demonstrates superior efficacy in:
- 5-FU chemotherapy adjuvant therapy (toxicity reduction)
- Methotrexate rescue therapy
- Megaloblastic anemia treatment
2.2 Biochemical Research
- Cell culture medium supplementation
- Enzyme reaction studies
- Folate metabolism research
3. Usage Scenarios and Best Practices
3.1 Oncology Protocols
Case Example: Combined with 5-Fluorouracil (5-FU) in colorectal cancer treatment:
- Dosage: 400 mg/m² IV pre-chemotherapy
- Result: 62% reduction in hematologic toxicity vs solo 5-FU
4. Verified Customer Success Stories
4.1 Nordic Pharma Solutions (Denmark)
- Application: Methotrexate overdose antidote production
- Outcome: 99.2% purity API achieved
- Volume: 850kg annual procurement
4.2 BioCell Research Consortium (USA)
- Application: Stem cell culture medium additive
- Result: 37% improvement in cell proliferation rates
5. Technical Support & Inquiry
Contact our experts for:
- Custom synthesis options
- Regulatory documentation
- Bulk pricing (100kg+ orders)
Email: info@vivalr.com
Tel: (86) 15866781826
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