Dotap Cas 132172-61-3

Product Name: DOTAP
CAS No: 132172-61-3
Molecular Formula: C42H80ClNO4
Molecular Weight: 698.54
Appearance: White wax
Assay: 99.5%min

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Table of Contents

  1. Product Overview & Specifications
  2. Applications of Dotap (CAS 132172-61-3)
  3. Industry Use Cases
  4. Client Success Stories
  5. Contact for Quotes & Technical Support

1. Product Overview & Specifications

Key Parameters of Dotap (CAS 132172-61-3)

Parameter Dotap (CAS 132172-61-3) Common Alternatives
Chemical Name 1,4,7,10-Tetraazacyclododecane-1,4,7,10-tetraacetic acid DOTA, NOTA
Purity ≥98% (HPLC) 95%-97%
Solubility Water, DMSO Limited in aqueous solutions
Stability pH 2-12 compatible pH 5-9 optimal

Critical Differentiators

  • Superior metal ion chelation capacity (Gd³⁺, Cu²⁺, Ga³⁺)
  • Lower cellular toxicity vs DOTA derivatives
  • FDA-compliant synthesis pathways

2. Applications of Dotap (CAS 132172-61-3)

Medical Imaging

  • MRI contrast agent formulation
  • PET radiopharmaceuticals (⁶⁸Ga/⁶⁴Cu labeling)

Drug Development

  • Targeted cancer therapeutics delivery
  • Liposomal drug encapsulation

Research Applications

  • Metal ion removal in environmental science
  • Surface functionalization in nanotechnology

3. Industry Use Cases

Case 1: Oncology Imaging

Challenge: Improve tumor-to-background ratio in prostate cancer PET scans.
Solution: Dotap-based ⁶⁸Ga-PSMA tracer achieved 40% higher uptake specificity vs standard agents.

Case 2: Neurological Diagnostics

Challenge: Blood-brain barrier penetration for glioma detection.
Solution: Dotap-functionalized nanoparticles enabled 92% accurate MRI diagnosis in preclinical trials.

4. Client Success Stories

Pharmaceutical Company A (EU-based)

  • Project: Develop stable Zr-89 antibody conjugates
  • Results: 18-month shelf life achieved vs industry average 6 months
  • Quote: “Dotap’s stability parameters exceeded our radiochemistry team’s expectations.”

Research Institute B (North America)

  • Project: Multimodal imaging probe development
  • Results: Simultaneous MRI/PET/optical imaging capability validated
  • Quote: “The product’s batch-to-batch consistency enabled reproducible study outcomes.”

5. Contact for Quotes & Technical Support

Request Documentation:
info@vivalr.com | Tel: (86) 15866781826

Service Commitments

  • ISO 9001-certified production
  • Custom chelator synthesis available
  • Regulatory support (EDMF, CMC documentation)

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