1-bromo-3,5-difluorobenzene cas 461-96-1

Chemical Name: 1-Bromo-3,5-difluorobenzene
CAS No.: 461-96-1
Molecular Formula: C6H3BrF2
Molecular weight: 192.99
Appearance: Colorless transparent liquid
Assay: ≥99%

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1-Bromo-3,5-Difluorobenzene (CAS 461-96-1) Comprehensive Guide

Table of Contents

1. Product Specifications

Parameter Specification Competitor A Competitor B
CAS Number 461-96-1 461-96-1 461-96-1
Purity ≥99.5% (HPLC) ≥98% ≥99%
Molecular Formula C6H3BrF2 Same formula
Melting Point 18-22°C 15-25°C 20-23°C

2. Key Applications

Pharmaceutical Intermediates

Critical building block for:

  • Anticancer drug candidates
  • EGFR kinase inhibitors
  • Fluorinated API development

Agrochemical Synthesis

Used in:

  • Herbicide precursors
  • Pesticide fluorination
  • Crop protection agents

3. Operational Guidelines

Handling Recommendations

  • Storage: 2-8°C in amber glass
  • Shelf Life: 24 months unopened
  • Incompatible with strong oxidizers

Reaction Optimization

Reaction Type Recommended Conditions
Suzuki Coupling Pd(PPh3)4, K2CO3, DMF/H2O
Buchwald-Hartwig XPhos Pd G3, Cs2CO3, toluene

4. Client Success Stories

Case Study 1: PharmaTech Solutions

  • Application: EGFR inhibitor development
  • Result: 92% yield improvement vs. alternative bromides
  • Scale: 150kg batch production

Case Study 2: AgroSolutions Ltd

  • Application: Novel herbicide synthesis
  • Outcome: 40% cost reduction in fluorination step
  • Volume: 500kg annual consumption

5. Request Custom Quote

Our technical team provides:

  • Batch-specific certificates of analysis
  • Regulatory support (REACH, TSCA compliant)
  • Custom packaging options

Contact our specialists:

Email: info@vivalr.com
Tel: (86) 15866781826

Why Choose Us?

Feature Benefit
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Just-in-Time Delivery 98.7% on-time shipment rate
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