1h-1,2,4-triazole-3-thiol cas 3179-31-5

Chemical Name: 1H-1,2,4-Triazole-3-thiolCAS No.:3179-31-5Molecular Fomula:C2H3N3S
Molecular Weight:101.13
Appearance:White or light yellow crystal
Assay: ≥99%

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1H-1,2,4-Triazole-3-thiol (CAS 3179-31-5) Technical Guide

1. Product Specifications & Comparative Analysis

Parameter Specification Industry Standard
Chemical Name 1H-1,2,4-Triazole-3-thiol Triazole derivatives
CAS Number 3179-31-5 N/A
Molecular Formula C2H3N3S Varies by compound
Molecular Weight 101.13 g/mol 80-120 g/mol (typical)
Appearance White to pale yellow crystalline powder Powder/Crystalline
Melting Point 218-221°C 200-250°C (triazole derivatives)
Solubility Water & ethanol soluble Polar solvent soluble

2. Industrial Applications

Core Functional Uses:

  • Pharmaceutical Intermediate: Key precursor in antiviral/anticancer drug synthesis
  • Corrosion Inhibition: Effective metal surface treatment agent (0.05-0.2% concentration)
  • Photochemical Applications: Photoinitiator in specialty imaging processes
  • Polymer Modification: Cross-linking agent for specialty resins

Performance Advantages:

  • Thermal stability up to 250°C
  • pH tolerance range: 3.5-9.0
  • Low environmental persistence (DT50 < 48hrs)

3. Operational Guidelines

Handling Protocol:

  1. Use NIOSH-approved PPE (N95 respirator, chemical gloves)
  2. Maintain ambient temperature storage (15-25°C)
  3. Implement inert atmosphere for high-purity applications
  4. Maximum working concentration: 5% w/v aqueous solution

Reaction Parameters:

Application Optimal Temperature Reaction Time Yield Efficiency
Drug Synthesis 60-80°C 4-6 hours 82-89%
Corrosion Formulation RT 30-45 min 95%+

4. Implementation Case Studies

Case A: Pharmaceutical Manufacturing

Challenge: Improve nucleoside analog synthesis efficiency
Solution: Implemented as coupling agent in step 3
Results: 18% yield improvement, 35% reduction in side products

Case B: Industrial Cooling Systems

Challenge: Copper alloy corrosion in heat exchangers
Solution: 0.1% additive in cooling water treatment
Results: 94% corrosion rate reduction (ASTM D1384)

5. Client Success Stories

Client 1: Specialty Chemical Manufacturer

  • Location: Wuhan, China
  • Application: High-purity drug intermediates
  • Outcome: Achieved 99.7% purity for EU market compliance

Client 2: Metal Treatment Facility

  • Location: Guangdong Province
  • Application: Automotive component preservation
  • Outcome: Extended part lifespan by 3.2x (salt spray test)

Technical Consultation & Bulk Orders:

Email: info@vivalr.com
Tel: (86) 15866781826

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