1. Product Overview & Specifications

2-Bromo-5-fluoropyridine (CAS 1003711-88-4) is a halogenated pyridine derivative with the molecular formula C₅H₃BrFN. It serves as a critical intermediate in organic synthesis.

Technical Specifications:

Comparative Analysis:

2. Key Applications

Pharmaceutical Intermediates

Used in synthesis of kinase inhibitors and antiviral agents through Suzuki-Miyaura cross-coupling reactions.

Agrochemical Development

Critical component in creating novel fungicides and herbicides with enhanced bioactivity.

Material Science

Building block for liquid crystals and conductive polymers in electronic applications.

3. Usage Guidelines

Suzuki Coupling Protocol

1. Charge reactor with 1.2 eq boronic acid
2. Add 0.5 mol% Pd catalyst
3. Maintain reaction at 80°C for 6h
4. Purify via column chromatography

Safety Precautions

• Use PPE (gloves, goggles)
• Avoid contact with strong oxidizers
• Store separately from amines

4. Case Studies

Anticancer Drug Intermediate

Used in 7-step synthesis of EGFR inhibitor (85% overall yield) with >99% chiral purity.

High-Performance Fungicide

Enabled creation of triazole derivative with 94% disease suppression at 50ppm concentration.

5. Client Success Stories

PharmaGen Solutions

“Achieved 30% cost reduction in kinase inhibitor production through optimized coupling reactions using 2-Bromo-5-fluoropyridine.”

AgroGuard Innovations

“Developed next-gen cereal fungicide with 2x field persistence compared to previous formulations.”

MaterialNano Tech

“Created OLED prototype with 15% improved luminous efficiency using fluoropyridine-based electron transport layer.”

6. Contact for Custom Solutions

Request bulk pricing or discuss custom synthesis:

info@vivalr.com
(86) 15866781826

Our technical team can develop:

• Custom halogenation patterns
• Isotope-labeled versions
• GMP-grade material